Evidence map›Paper›PMID 34143951›Full record

ReviewNeuron2021

Promises and challenges of human computational ethology.

Dean Mobbs, Toby Wise, Nanthia Suthana, Noah Guzmán, Nikolaus Kriegeskorte, Joel Z Leibo

Abstract readReview
In one paragraph

Review in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Trial
  2. Towards Human-Centered Digital Health Interventions.The Psychiatric clinics of North America · 2026
    Review
  3. Article
  4. Rethinking Ethics for an Era of Trusted Computational Tools.The Psychiatric clinics of North America · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Fear, anxiety, and the extended amygdala-bioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Naturalistic reinforcement learning.Trends in cognitive sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dean MobbsDepartment of Humanities and Social Sciences, 1200 E. California Blvd., HSS 228-77, Pasadena, CA 91125, USA; Computation and Neural Systems Program at the California Institute of Technology, 1200 E. California Blvd., HSS 228-77, Pasadena, CA 91125, USA. Electronic address: dmobbs@caltech.edu.
Toby WiseDepartment of Humanities and Social Sciences, 1200 E. California Blvd., HSS 228-77, Pasadena, CA 91125, USA; Wellcome Centre for Human Neuroimaging, University College London, London, UK; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, University College London, London, UK.
Nanthia SuthanaDepartment of Psychiatry and Biobehavioral Sciences, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA; Departments of Neurosurgery, Psychology, and Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA.
Noah GuzmánComputation and Neural Systems Program at the California Institute of Technology, 1200 E. California Blvd., HSS 228-77, Pasadena, CA 91125, USA.
Nikolaus KriegeskorteDepartment of Psychology, Columbia University, New York, NY, USA; Department of Neuroscience, Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Joel Z LeiboDeepMind, London, UK.

Funding

The Neurobiology of Social Decision-Making: Social Inference and ContextP50MH094258 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ADOLPHS, RALPH · 2012 to 2021
$18.6M
Neurostimulation and Recording of Real World Spatial Navigation in HumansU01NS117838 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUTHANA, NANTHIA A · 2020 to 2024
$5.3M
Neurostimulation and Recording of Real World Spatial Navigation in HumansU01NS103802 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUTHANA, NANTHIA A · 2017 to 2019
$3.4M
Predoctoral Training in Quantitative NeuroscienceT32NS105595 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI MARKUS MEISTER · 2019 to 2026
$2.6M
NIMH NIH HHS P50 MH094258NINDS NIH HHS T32 NS105595NINDS NIH HHS U01 NS103802NINDS NIH HHS U01 NS117838Wellcome TrustWellcome Trust 206460/17/Z
6 · The paper itself

Abstract

The movements an organism makes provide insights into its internal states and motives. This principle is the foundation of the new field of computational ethology, which links rich automatic measurements of natural behaviors to motivational states and neural activity. Computational ethology has proven transformative for animal behavioral neuroscience. This success raises the question of whether rich automatic measurements of behavior can similarly drive progress in human neuroscience and psychology. New technologies for capturing and analyzing complex behaviors in real and virtual environments enable us to probe the human brain during naturalistic dynamic interactions with the environment that so far were beyond experimental investigation. Inspired by nonhuman computational ethology, we explore how these new tools can be used to test important questions in human neuroscience. We argue that application of this methodology will help human neuroscience and psychology extend limited behavioral measurements such as reaction time and accuracy, permit novel insights into how the human brain produces behavior, and ultimately reduce the growing measurement gap between human and animal neuroscience.

Indexed as

BrainCognitionEthologyHumansNeurosciences

Identifiers

PMID34143951
PMCPMC8769712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.