Evidence map›Paper›PMID 34143842›Full record

ArticlePloS one2021

Inter-hospital transfer of polytrauma and severe traumatic brain injury patients: Retrospective nationwide cohort study using data from the Swiss Trauma Register.

Rebecca M Hasler, Thomas Rauer, Hans-Christoph Pape, Marcel Zwahlen

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Transport and destination hospital for patients with suspected multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Pooled it
  2. Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries - A systematic review of the literature by the IMPACT group.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  3. Guideline
  4. Article
  5. Independence of the mortality of severely injured patients from types of transport and hospital level in a well-developed trauma network.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rebecca M HaslerDepartment of Traumatology, University Hospital Zürich, Zürich, Switzerland.ORCID 0000-0002-0616-2313
Thomas RauerDepartment of Traumatology, University Hospital Zürich, Zürich, Switzerland.ORCID 0000-0003-4775-1103
Hans-Christoph PapeDepartment of Traumatology, University Hospital Zürich, Zürich, Switzerland.
Marcel ZwahlenInstitute of Social and Preventive Medicine (ISPM), Bern University, Bern, Switzerland.ORCID 0000-0002-6772-6346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPolytrauma and traumatic brain injury (TBI) patients are among the most vulnerable patients in trauma care and exhibit increased morbidity and mortality. Timely care is essential for their outcome. Severe TBI with initially high scores on the Glasgow Coma (GCS) scores is difficult to recognise on scene and referral to a Major Trauma Center (MTC) might be delayed. Therefore, we examined current referral practice, injury patterns and mortality in these patients. MATERIALS AND

methodsRetrospective, nationwide cohort study with Swiss Trauma Register (STR) data between 01/012015 and 31/12/2018. STR includes patients ≥16 years with an Injury Severity Score (ISS) >15 and/or an Abbreviated Injury Scale (AIS) for head >2. We performed Cox proportional hazard models with injury type as the primary outcome and mortality as the dependent variable. Secondary outcomes were inter-hospital transfer and age.

results9,595 patients were included. Mortality was 12%. 2,800 patients suffered from isolated TBI. 69% were men. Median age was 61 years and median ISS 21. Two thirds of TBI patients had a GCS of 13-15 on admission to the Emergency Department (ED). 26% of patients were secondarily transferred to an MTC. Patients with isolated TBI and those aged ≥65 years were transferred more often. Crude analysis showed a significantly elevated hazard for death of 1.48 (95%CI 1.28-1.70) for polytrauma patients with severe TBI and a hazard ratio (HR) of 1.82 (95%CI 1.58-2.09) for isolated severe TBI, compared to polytrauma patients without TBI. Patients directly admitted to the MTC had a significantly elevated HR for death of 1.63 (95%CI 1.40-1.89), compared to those with secondary transfer.

conclusionsA high initial GCS does not exclude the presence of severe TBI and triage to an MTC should be seriously considered for elderly TBI patients.

Indexed as

Patient TransferAdolescentAdultAgedAged, 80 and overBrain Injuries, TraumaticCohort StudiesFemaleHumansInjury Severity ScoreMaleMiddle AgedMultiple TraumaRegistriesRetrospective StudiesSwitzerland

Identifiers

PMID34143842
PMCPMC8213144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.