ArticleeLife2021
Protective function and durability of mouse lymph node-resident memory CD8
Open access · goldAbstract read
In one paragraph
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Chitosan-based hydrogel facilitates DC-SIGN-mediated monocyte-to-dendritic cell transformation in vivo for antigen-specific antitumor therapy.Materials today. Bio · 2026Article
- Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunction.bioRxiv : the preprint server for biology · 2026Article
- The ability of memory CD8 T cell subsets to numerically and functionally recover following whole body irradiation is influenced by their history of cognate antigen exposures.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Review
- Physiological microbial exposure normalizes memory T cell surveillance of the brain and modifies host seizure outcomes.Nature immunology · 2025Article
- Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8Cell reports · 2025Article
- The 41BB-agonist potentiates the therapeutic efficacy of a combined irreversible electroporation ablation treatment of lung cancer by promoting unexpected CD8Frontiers in immunology · 2025Article
- Airway-resident memory CD4 T cell activation accelerates antigen presentation and T cell priming in draining lymph nodes.JCI insight · 2024Article
- Dynamic landscapes and protective immunity coordinated by influenza-specific lung-resident memory CD8Immunity · 2024Article
- Efficient enzyme-free method to assess the development and maturation of the innate and adaptive immune systems in the mouse colon.Scientific reports · 2024Article
- Regenerating murine CD8+ lung tissue resident memory T cells after targeted radiation exposure.The Journal of experimental medicine · 2024Article
- A novel "prime and pull" strategy mediated by the combination of two dendritic cell-targeting designs induced protective lung tissue-resident memory T cells against H1N1 influenza virus challenge.Journal of nanobiotechnology · 2023Article
- Lung cDC1 and cDC2 dendritic cells priming naive CD8Cell reports · 2023Article
- Review
- IKK2/NFkB signaling controls lung resident CD8Nature communications · 2023Article
- Unique properties of tissue-resident memory T cells in the lungs: implications for COVID-19 and other respiratory diseases.Nature reviews. Immunology · 2023Review
- Inefficient Recovery of Repeatedly Stimulated Memory CD8 T Cells after Polymicrobial Sepsis Induction Leads to Changes in Memory CD8 T Cell Pool Composition.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- The transcriptomics profiling of blood CD4 and CD8 T-cells in narcolepsy type I.Frontiers in immunology · 2023Article
- Sepsis-induced changes in differentiation, maintenance, and function of memory CD8 T cell subsets.Frontiers in immunology · 2023Review
- Influenza-Induced CD103ImmunoHorizons · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 1 institution in 1 country.
Scott M Anthony *Department of Pathology, The University of Iowa, Iowa City, United States.ORCID 0000-0002-1590-7401
Natalija Van Braeckel-Budimir *Department of Pathology, The University of Iowa, Iowa City, United States.
Steven J MoiofferDepartment of Pathology, The University of Iowa, Iowa City, United States.
Stephanie van de WallDepartment of Pathology, The University of Iowa, Iowa City, United States.
Qiang ShanDepartment of Microbiology and Immunology, The University of Iowa, Iowa City, United States.
Rahul VijayDepartment of Microbiology and Immunology, The University of Iowa, Iowa City, United States.
Ramakrishna SompallaeDepartment of Pathology, The University of Iowa, Iowa City, United States.
Stacey M HartwigDepartment of Microbiology and Immunology, The University of Iowa, Iowa City, United States.
Isaac J JensenDepartment of Pathology, The University of Iowa, Iowa City, United States.ORCID 0000-0002-3107-3961
Steven M VargaDepartment of Pathology, The University of Iowa, Iowa City, United States.
Noah S ButlerDepartment of Microbiology and Immunology, The University of Iowa, Iowa City, United States.ORCID 0000-0002-1429-0796
Hai-Hui XueDepartment of Microbiology and Immunology, The University of Iowa, Iowa City, United States.ORCID 0000-0002-9163-7669
Vladimir P BadovinacDepartment of Pathology, The University of Iowa, Iowa City, United States.ORCID 0000-0003-3180-2439
John T HartyDepartment of Pathology, The University of Iowa, Iowa City, United States.ORCID 0000-0001-7266-2802
University of Iowa · US
Funding
TRAINING IN MECHANISMS OF PARASITISMT32AI007511 · NIAID · UNIVERSITY OF IOWA · PI BUTLER, NOAH SULLIVAN, WEBER, MARY · 1996 to 2025
$8.1MINTERDISCIPLINARY IMMUNOLOGY TRAINING PROGRAMT32AI007260 · NIAID · UNIVERSITY OF IOWA · PI BUTLER, NOAH SULLIVAN, WU, LI · 1986 to 2023
$5.7MRegulation of primary and secondary CD4 and CD8 T cell memoryR37AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2008 to 2017
$4.7MTcf/Lef and B-catenin pathway in follicular helper T cellsR01AI121080 · NIAID · UNIVERSITY OF IOWA · PI Hai-Hui Xue · 2016 to 2026
$4.6MMemory CD8 T cell localization and protection from influenzaR01AI114543 · NIAID · UNIVERSITY OF IOWA · PI BADOVINAC, VLADIMIR P, HARTY, JOHN T · 2015 to 2024
$4.4MT resident memory in the lungR01AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 1998 to 2023
$4.4MRegulation of Plasmodium-specific CD4+ T CellsR01AI127481 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Noah Sullivan Butler · 2016 to 2026
$3.8MDevelopment and function of CD4+ memory T cells during malariaR01AI125446 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Noah Sullivan Butler · 2016 to 2026
$3.7MEzh2 regulates follicular helper T cell differentiationR01AI139874 · NIAID · UNIVERSITY OF IOWA · PI PENG, WEIQUN, XUE, HAI-HUI · 2018 to 2022
$2.4MCellular and molecular mechanisms controlling sepsis-induced immunoparalyses stateR35GM134880 · NIGMS · UNIVERSITY OF IOWA · PI BADOVINAC, VLADIMIR P · 2020 to 2024
$1.9MBalancing protection versus immunopathology by RSV-specific memory CD8 T cellsR01AI124093 · NIAID · UNIVERSITY OF IOWA · PI VARGA, STEVEN M · 2017 to 2020
$1.6MCD8+ T Cell effector mechanisms against L. monocytogenesR21AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T. · 2002 to 2002
$331kBLRD VA I01 BX002903NIAID NIH HHS R01 AI042767NIAID NIH HHS R01 AI114543NIAID NIH HHS R01 AI121080NIAID NIH HHS R01 AI124093NIAID NIH HHS R01 AI125446NIAID NIH HHS R01 AI127481NIAID NIH HHS R01 AI139874NIAID NIH HHS R21 AI042767NIAID NIH HHS R37 AI042767NIAID NIH HHS T32 AI007260NIAID NIH HHS T32 AI007511NIGMS NIH HHS R35 GM134880
Abstract
Protective lung tissue-resident memory CD8
Indexed as
CD8-Positive T-LymphocytesLymph NodesAnimalsAntigens, CDCells, CulturedFemaleInfluenza A virusLungMiceMice, Inbred C57BLOrthomyxoviridae InfectionsTranscriptomeAntigens, CDCD8+ T cellCD8+ T cell resident memoryimmunologyinflammationlunglymph nodemouserepeated antigen exposurevirus infection
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.