Evidence map›Paper›PMID 34143508›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2021

Benign course and clinical features of COVID-19 in hospitalised febrile infants up to 60 days old.

Havazelet Yarden Bilavski, Sarit Balanson, Ranaa Damouni Shalabi, Halima Dabaja-Younis, Galia Grisaru-Soen, Ilan Youngster, Daniel Glikman, Shalom Ben Shimol, Eli Somech, Diana Tasher and 4 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Havazelet Yarden BilavskiDepartment of Pediatrics A, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Sarit BalansonDepartment of Pediatrics A, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.ORCID https://orcid.org/0000-0003-4721-5933
Ranaa Damouni ShalabiPediatric Infectious Diseases, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa, Israel.
Halima Dabaja-YounisPediatric Infectious Diseases, Ruth Rappaport Children's Hospital, Rambam Health Care Campus, Haifa, Israel.ORCID https://orcid.org/0000-0001-9028-3195
Galia Grisaru-SoenPediatric Infectious Disease Unit, Tel Aviv Sourasky Medical Center, Dana-Dwek Children's Hospital, Sackler Faculty of Medicine, Tel Aviv, Israel.
Ilan YoungsterPediatric Infectious diseases unit, Shamir Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Daniel GlikmanInfectious Diseases Unit, Padeh Poria Medical Center, Poria, Israel.ORCID https://orcid.org/0000-0002-8006-5845
Shalom Ben ShimolPediatric Infectious Disease Unit, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University, Beer Sheva, Israel.
Eli SomechDepartment of Pediatrics, Mayaney Hayeshuah Medical Center, Bnei Brak and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Diana TasherPediatric Infectious Diseases Unit, Wolfson Medical Center, Holon and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Michal SteinInfectious Disease & Infection Control Unit, Hillel Yafe Medical Center, Hadera, Israel.ORCID https://orcid.org/0000-0002-0765-7326
Giora GottesmanmMeir Medical Center, Kfar Saba, Israel.
Gilat LivniDepartment of Pediatrics A, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Orli MeggedDepartment of Pediatrics A, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Schneider Children's Medical Center · ILTel Aviv University · ILRambam Health Care Campus · ILBar-Ilan University · ILSoroka Medical Center · ILTechnion – Israel Institute of Technology · ILTel Aviv Sourasky Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimMinimal data exist regarding the severity of COVID-19 in febrile infants under 60 days old. This multicentre prospective study explored the clinical course and outcomes of this hospitalised patient population, as, to date, the best approach has not been specifically addressed.

methodsThis study focused on the clinical features, laboratory parameters and outcomes of febrile infants up to 60 days old who tested positive for the virus and were hospitalised in Israel from March 2020 to January 2021. The data were extracted from a real-time prospective surveillance network for COVID-19 that includes 20 of the country's 26 hospitals.

resultsWe identified 75 febrile young infants (60% female) with COVID-19 at a median age of 28 days (range 8-56 days). Of these, 84% had an unremarkable medical history, 29% had respiratory symptoms, and 96% had a mild illness. The Rochester criteria showed that 44% were considered at high-risk for serious bacterial infections, and we found that eight infants actually had concomitant bacterial infections. Outcomes were excellent, and no complications or fatalities were reported.

conclusionThe excellent outcomes of young febrile infants with COVID-19 closely resembled other respiratory viral aetiologies of fever in this age group, and there were no fatalities.

Indexed as

Bacterial InfectionsCOVID-19FemaleFeverHumansInfantMaleProspective StudiesSARS-CoV-2COVID-19infantsneonatal feverRochester criteriaserious bacterial infection

Identifiers

PMID34143508
PMCPMC8444866
OpenAlexW3171721633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.