Evidence map›Paper›PMID 34143394›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2021

Canadian Airway Focus Group updated consensus-based recommendations for management of the difficult airway: part 1. Difficult airway management encountered in an unconscious patient.

J Adam Law, Laura V Duggan, Mathieu Asselin, Paul Baker, Edward Crosby, Andrew Downey, Orlando R Hung, Philip M Jones, François Lemay, Rudiger Noppens and 8 more

2 registry-linked trialsOpen access · hybridAbstract readConsensus Statement
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 72 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 5 pooled it
25.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05535127 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Sequential Strategy of Palpation Plus Ultrasound vs Palpation vs Routine Ultrasound , in Adults for Detection of Cricothyroid Membrane: Protocol of an Adaptive Controlled Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AntioquiaRan2022 to 2023Enrolled258ConditionsAirway Disease, Intubation, Difficult or Failed, Ultrasound TherapyArmsPalpation with " laryngeal handshake" technique, Palpation strategy plus sequential ultrasound, Identification of the cricothyroid membrane with routine ultrasound
NCT06676462 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Pilot Study Comparing the HEINE visionPRO HyMac 3 and the GlideScope Hyperangulated S3 Laryngoscope Blade on Time to Intubation

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2025 to 2027Enrolled100ConditionsIntubation, Difficult or Failed, Intubation Complication, Video LaryngoscopyArmsVideo laryngoscopy with visionPRO, Video laryngoscopy with Glidescope
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 5 syntheses or guidelines pooled it, 161 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Guideline
  5. Awake Versus Asleep Intubation for Mediastinal Goiters: A Systematic Review and Meta-Analysis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Comparison of the effects of paratracheal pressure and cricoid pressure on placement of the i-gelCanadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Trial
  10. Trial
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Observational
  16. Article
  17. Airway management skills and devices on Italian helicopter emergency medical service: a national survey.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026
    Observational
  18. Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 3 countries.

J Adam LawDepartment of Anesthesia, Pain Management and Perioperative Medicine, QEII Health Sciences Centre, Dalhousie University, Halifax Infirmary Site, 1796 Summer Street, Room 5452, Halifax, NS, B3H 3A7, Canada. jlaw@dal.ca.ORCID http://orcid.org/0000-0003-3916-3918
Laura V DugganDepartment of Anesthesiology and Pain Medicine, The Ottawa Hospital Civic Campus, University of Ottawa, Room B307, 1053 Carling Avenue, Mail Stop 249, Ottawa, ON, K1Y 4E9, Canada.
Mathieu AsselinDépartement d'anesthésiologie et de soins intensifs, Université Laval, 2325 rue de l'Université, Québec, QC, G1V 0A6, Canada.
Paul BakerDepartment of Anaesthesiology, Faculty of Medical and Health Science, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.
Edward CrosbyDepartment of Anesthesiology and Pain Medicine, The Ottawa Hospital, University of Ottawa, Suite CCW1401, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
Andrew DowneyDepartment of Anaesthesia, Perioperative and Pain Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia.
Orlando R HungDepartment of Anesthesia, Pain Management and Perioperative Medicine, QEII Health Sciences Centre, Dalhousie University, 1796 Summer Street, Halifax, NS, B3H 3A7, Canada.
Philip M JonesDepartment of Anesthesia & Perioperative Medicine, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, University of Western Ontario, LHSC- University Hospital, 339 Windermere Rd., London, ON, N6A 5A5, Canada.
François LemayDépartement d'anesthésiologie, CHU de Québec - Université Laval, Hôtel-Dieu de Québec, 11, Côte du Palais, Québec, QC, G1R 2J6, Canada.
Rudiger NoppensDepartment of Anesthesia & Perioperative Medicine, Schulich School of Medicine & Dentistry, University of Western Ontario, LHSC- University Hospital, 339 Windermere Road, London, ON, N6A 5A5, Canada.
Matteo ParottoDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto General Hospital, Toronto, ON, Canada.
Roanne PrestonDepartment of Anesthesia, BC Women's Hospital, 4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.
Nick SowersDepartment of Emergency Medicine, QEII Health Sciences Centre, Dalhousie University, 1796 Summer Street, Halifax, NS, B3H 3A7, Canada.
Kathryn SparrowDiscipline of Anesthesia, St. Clare's Mercy Hospital, Memorial University of Newfoundland, 300 Prince Phillip Drive, St. John's, NL, A1B V6, Canada.
Timothy P TurkstraDepartment of Anesthesia & Perioperative Medicine, Schulich School of Medicine & Dentistry, University of Western Ontario, LHSC- University Hospital, 339 Windermere Road, London, ON, N6A 5A5, Canada.
David T WongDepartment of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, 399, Bathurst St, Toronto, ON, M5T2S8, Canada.
George KovacsDepartment of Emergency Medicine, QEII Health Sciences Centre, Dalhousie University, 1796 Summer Street, Halifax, NS, B3H 3A7, Canada.
Canadian Airway Focus Group
Dalhousie University · CAWestern University · CAUniversity of Ottawa · CAB.C. Women's Hospital & Health Centre · CAHôpital de l'Enfant-Jésus · CAHôtel-Dieu de Québec · CAMemorial University of Newfoundland · CAPeter MacCallum Cancer Centre · AUUniversity Health Network · CAUniversity of Auckland · NZUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSince the last Canadian Airway Focus Group (CAFG) guidelines were published in 2013, the literature on airway management has expanded substantially. The CAFG therefore re-convened to examine this literature and update practice recommendations. This first of two articles addresses difficulty encountered with airway management in an unconscious patient. SOURCE: Canadian Airway Focus Group members, including anesthesia, emergency medicine, and critical care physicians, were assigned topics to search. Searches were run in the Medline, EMBASE, Cochrane Central Register of Controlled Trials, and CINAHL databases. Results were presented to the group and discussed during video conferences every two weeks from April 2018 to July 2020. These CAFG recommendations are based on the best available published evidence. Where high-quality evidence was lacking, statements are based on group consensus. FINDINGS AND KEY RECOMMENDATIONS: Most studies comparing video laryngoscopy (VL) with direct laryngoscopy indicate a higher first attempt and overall success rate with VL, and lower complication rates. Thus, resources allowing, the CAFG now recommends use of VL with appropriately selected blade type to facilitate all tracheal intubations. If a first attempt at tracheal intubation or supraglottic airway (SGA) placement is unsuccessful, further attempts can be made as long as patient ventilation and oxygenation is maintained. Nevertheless, total attempts should be limited (to three or fewer) before declaring failure and pausing to consider "exit strategy" options. For failed intubation, exit strategy options in the still-oxygenated patient include awakening (if feasible), temporizing with an SGA, a single further attempt at tracheal intubation using a different technique, or front-of-neck airway access (FONA). Failure of tracheal intubation, face-mask ventilation, and SGA ventilation together with current or imminent hypoxemia defines a "cannot ventilate, cannot oxygenate" emergency. Neuromuscular blockade should be confirmed or established, and a single final attempt at face-mask ventilation, SGA placement, or tracheal intubation with hyper-angulated blade VL can be made, if it had not already been attempted. If ventilation remains impossible, emergency FONA should occur without delay using a scalpel-bougie-tube technique (in the adult patient). The CAFG recommends all institutions designate an individual as "airway lead" to help institute difficult airway protocols, ensure adequate training and equipment, and help with airway-related quality reviews.

Indexed as

Airway ManagementIntubation, IntratrachealAdultCanadaFocus GroupsHumansLaryngoscopyairway managementdifficultfailedguidelinesintubationtracheal

Identifiers

PMID34143394
PMCPMC8212585
OpenAlexW3168446116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.