Evidence map›Paper›PMID 34143349›Full record

ArticleOdontology2022

An in vitro senescence model of gingival epithelial cell induced by hydrogen peroxide treatment.

Sarita Giri, Ayuko Takada, Durga Paudel, Koki Yoshida, Masae Furukawa, Yasuhiro Kuramitsu, Kenji Matsushita, Yoshihiro Abiko, Yasushi Furuichi

Abstract read
PubMed Publisher
In one paragraph

Article in Odontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Infection and immunity · 2026
    Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sarita GiriDivision of Periodontology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, 061-0293, Japan.
Ayuko TakadaDivision of Biochemistry, Department of Oral Biology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Durga PaudelDivision of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Koki YoshidaDivision of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Masae FurukawaDepartment of Oral Disease Research, National Center for Geriatrics and Gerontology, Obu, Japan.
Yasuhiro KuramitsuResearch Institute of Cancer Prevention, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Kenji MatsushitaDepartment of Oral Disease Research, National Center for Geriatrics and Gerontology, Obu, Japan.
Yoshihiro AbikoDivision of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan.
Yasushi FuruichiDivision of Periodontology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Ishikari-Tobetsu, 061-0293, Japan. furuichi@hoku-iryo-u.ac.jp.
Health Sciences University of Hokkaido · JPNational Center for Geriatrics and Gerontology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gingival tissue shows progressive changes with aging and an in vitro model of gingival tissue could be useful in understanding age-associated oral diseases. The present study aims to establish a hydrogen peroxide (H

Indexed as

Cellular SenescenceHydrogen PeroxideCells, CulturedEpithelial CellsGingivaHumansHydrogen PeroxideAgingAntioxidantsHydrogen peroxideOxidative stressPeriodontium

Identifiers

PMID34143349
OpenAlexW3173128792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.