ArticleJournal of gastroenterology2021
A simple prediction score for in-hospital mortality in patients with nonvariceal upper gastrointestinal bleeding.
Article in Journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pooled it
- Non-variceal upper gastrointestinal bleeding: advances and future directions in management.Clinical endoscopy · 2026Review
- Distinct clinical course and poor outcomes of small bowel bleeding in acute hematochezia: a nationwide multicenter study.Scientific reports · 2026Article
- Comparative predictive value of AIMS65, Pre-endoscopic Rockall and Glasgow-Blatchford Scoring Systems in Nonvariceal Upper Gastrointestinal Bleeding.Pakistan journal of medical sciences · 2026Article
- Development, validation, and web deployment of a rebleeding risk prediction model for acute non-variceal upper gastrointestinal bleeding in a Chinese population.Frontiers in medicine · 2025Article
- Risk stratification and scoring systems in upper and lower gastrointestinal bleeding: review of performance and limitations in the emergency department.Frontiers in medicine · 2025Review
- Construction of a predictive model for rebleeding risk in upper gastrointestinal bleeding patients based on clinical indicators such asFrontiers in microbiology · 2025Article
- Comparison and validation of several scoring systems for non-variceal upper gastrointestinal bleeding: a retrospective study.Scientific reports · 2024Article
- Development of a prediction score for Barrett's esophagus in Japanese health checkup settings.Esophagus : official journal of the Japan Esophageal Society · 2024Article
- Similar Effect of Vonoprazan and Oral Proton Pump Inhibitors for Preventing Rebleeding in Cases of Upper Gastrointestinal Bleeding.Internal medicine (Tokyo, Japan) · 2024Article
- Risk factors for rebleeding in gastroduodenal ulcers.Irish journal of medical science · 2024Article
- Validating the CHAMPS Score: A Novel and Reliable Prognostic Score of Non-Variceal Upper Gastrointestinal Bleeding.Clinical and experimental gastroenterology · 2024Article
- Pre-Endoscopic Scores Predicting Low-Risk Patients with Upper Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Real-world efficacy of antibiotic prophylaxis for upper gastrointestinal bleeding in cirrhotic patients in Japan.Journal of gastroenterology · 2023Article
- Article
- Clinical Outcomes of Patients with Benign Peptic Ulcer Bleeding After an Emergency Endoscopy Based on Patient Location.Digestive diseases and sciences · 2023Article
- CHAMPS score in predicting mortality of patients with acute nonvariceal upper gastrointestinal bleeding.Revista da Associacao Medica Brasileira (1992) · 2023Article
- Nature and Clinical Outcomes of Acute Hemorrhagic Rectal Ulcer.Diagnostics (Basel, Switzerland) · 2022Article
- Usefulness of the CHAMPS score for risk stratification in lower gastrointestinal bleeding.Scientific reports · 2022Article
- A New Preoperative Scoring System for Predicting Aggressiveness of Non-Functioning Pancreatic Neuroendocrine Neoplasms.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
26 authors at 12 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo prediction scores for the mortality of both inpatients and outpatients who developed nonvariceal upper gastrointestinal bleeding (UGIB) without endoscopic findings have been established. We aimed to derive and validate a novel prediction score for in-hospital mortality.
methodsWe conducted a three-stage, multicenter retrospective study. In the derivation stage, patients with nonvariceal UGIB at six institutions were enrolled to derive the prediction score by logistic regression analysis. External validation of the score was performed to analyze discrimination by patients at six other institutions. Then the performance of this score was compared with that of four existing scores.
resultsWe enrolled 1380 and 825 patients in the derivation and validation cohorts, respectively. A prediction score (CHAMPS-R Score) comprising seven variables (Charlson Comorbidity Index ≥ 2, in-hospital onset, albumin < 2.5 g/dL, altered mental status, Eastern Cooperative Oncology Group performance status ≥ 2, steroids, and rebleeding) with equal-weight scores was established, with high discriminative ability in both derivation and validation cohorts (c statistic, 0.91 and 0.80, respectively). When rebeeding was excluded from the score (an onset model; CHAMPS Score), this score also achieved high discriminative ability (c statistic, 0.90 and 0.81, respectively). The prediction scores had significantly higher discriminative ability than the Glasgow Blatchford Score, AIMS65, ABC Score, and clinical Rockall Score in both cohorts (all, p < 0.05).
conclusionsWe derived and externally validated prediction scores for in-hospital mortality in patients with nonvariceal UGIB. The CHAMPS Score might be optimal for managing such patients. Its mobile application is freely available ( https://apps.apple.com/app/id1565716902 for iOS and https://play.google.com/store/apps/details?id=hatta.CHAMPS for Android).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.