Evidence map›Paper›PMID 34143305›Full record

ArticleEuropean journal of applied physiology2021

Relating cardiorespiratory responses to work rate during incremental ramp exercise on treadmill in children and adolescents: sex and age differences.

Nicola Lai, Justin J Fiutem, Nora Pfaff, Desy Salvadego, James Strainic

Open access · hybridAbstract read
In one paragraph

Article in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Nicola LaiDepartment of Mechanical, Chemical and Materials Engineering, University of Cagliari, Cagliari, Italy. nicola.lai@unica.it.ORCID http://orcid.org/0000-0002-3436-289X
Justin J FiutemDepartments of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
Nora PfaffDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Desy SalvadegoDepartment of Automation, Biocybernetics and Robotics, Jožef Stefan Institute, Ljubljana, Slovenia.
James StrainicDepartments of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
Rainbow Babies & Children's Hospital · USJožef Stefan Institute · SIUniversity of Cagliari · ITUniversity of California, San Francisco · US

Funding

CORE--SYSTEM MODELING INTEGRATIONP50GM066309 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI SAIDEL, GERALD M · 2002 to 2006
$11.4M
Systems Biology Investigation of Muscle Exercise Metabolism in DiabetesK25AR057206 · NIAMS · OLD DOMINION UNIVERSITY · PI LAI, NICOLA · 2011 to 2015
$593k
NIAMS NIH HHS K25 AR057206NIAMS NIH HHS K25AR057206NIGMS NIH HHS GM6630901
6 · The paper itself

Abstract

purposeEvaluation of cardiopulmonary exercise testing (CPET) slopes such as [Formula: see text] (cardiac/skeletal muscle function) and [Formula: see text] (O

methodsCPET's were performed by healthy patients, (n = 674, 9-18 year) 300 female (F) and 374 male (M), using an incremental ramp protocol on a treadmill. For this protocol, a quantitative relationship based on biomechanical principles of human locomotion, was used to quantify the [Formula: see text] of the subject. CPET slopes were determined by linear regression of the data recorded until the gas exchange threshold occurred.

resultsThe method to estimate [Formula: see text] was substantiated by verifying that: [Formula: see text] for treadmill exercise corresponded to an efficiency of muscular work similar to that of cycle ergometer; [Formula: see text] (mL min

conclusionThe proposed approach can be used to estimate [Formula: see text] and quantify CPET slopes derived from incremental ramp protocols at submaximal exercise intensities using the treadmill, like the cycle ergometer, to infer cardiovascular and metabolic function in both healthy and diseased states.

Indexed as

Age FactorsSex FactorsAdolescentChildExerciseExercise TestFemaleHeart RateHumansMaleMuscle, SkeletalOxygen ConsumptionPhysical ExertionCPET slopesExternal work rateKineticsMuscular efficiencyOxygen delivery

Identifiers

PMID34143305
PMCPMC8416851
OpenAlexW3172299652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.