ReviewInternational journal of colorectal disease2021
Classification of acute appendicitis (CAA): treatment directed new classification based on imaging (ultrasound, computed tomography) and pathology.
Review in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Clinical efficacy and safety of endoscopic retrograde appendicitis treatment for acute appendicitis in children: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2025Pooled it
- Abdominal drainage to prevent intraperitoneal abscess after appendectomy for complicated appendicitis.The Cochrane database of systematic reviews · 2025Pooled it
- Appendiceal abscess: pathologic definitions and a diagnostic framework-SIRC/SICUT consensus.International journal of colorectal disease · 2026Article
- Routine Biomarkers in Paediatric Appendicitis Stratification: Which Add Diagnostic Value? A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Epidemiology and histopathological spectrum of appendiceal pathologies in 40.286 adults: a multicenter study from Turkey (2017-2025).European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- A novel combined neutrophil-platelet score for diagnosing complicated appendicitis: a retrospective and prospective cohort study.Acta cirurgica brasileira · 2026Article
- Development and validation of a diagnostic nomogram based on peripheral blood composite inflammatory markers for complicated acute appendicitis: a retrospective study.Frontiers in surgery · 2026Article
- Retrospective analysis of 331 acute appendicitis patients: how appendicolith and CT features aid in differentiating complicated vs. uncomplicated appendicitis.BMC gastroenterology · 2025Article
- Progress in the application of machine learning in CT diagnosis of acute appendicitis.Abdominal radiology (New York) · 2025Review
- Diagnostic efficacy, imaging characteristics, and detection accuracy of transabdominal superficial ultrasonography for various types of appendicitis.World journal of gastrointestinal surgery · 2025Article
- Laparoscopic appendectomy as the gold standard: What role remains for open surgery, conversion, and disease severity? : An analysis of 32,000 cases with appendicitis in Germany.World journal of emergency surgery : WJES · 2025Observational
- Phlegmonous appendicitis as a variant of uncomplicated appendicitis.Scientific reports · 2025Article
- C-Reactive Protein, International Normalized Ratio, and Fibrinogen in Diagnostic Scale of Complicated Acute Appendicitis.Clinics and practice · 2025Article
- Update on the Diagnosis and Treatment of Acute Appendicitis.Journal of clinical medicine · 2024Article
- Inflammatory Signals Across the Spectrum: A Detailed Exploration of Acute Appendicitis Stages According to EAES 2015 Guidelines.Diagnostics (Basel, Switzerland) · 2024Article
- Comparative study of imaging features in uncomplicated and complicated acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Observational
- Is appendoscope a new option for the treatment of acute appendicitis?World journal of gastroenterology · 2024Review
- Clinical Scoring Systems to Diagnose Complicated Acute Appendicitis in a Rural Hospital: Are They Good Enough?Cureus · 2024Article
- Early versus delayed appendicectomy for appendiceal phlegmon or abscess.The Cochrane database of systematic reviews · 2024Review
- Identification of complicated and non-complicated appendicitis: a new alvarado-based scoring system.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAcute appendicitis (AA) is amongst the most common causes of acute abdominal pain. In spite of progress based on risk stratifications, "negative" appendectomies are performed in up to 30% of patients whilst the appendix perforates in others. Preoperative classification of AA based on imaging is therefore recommended. The aim was to classify AA based on imaging (ultrasound/US, computed tomography/CT), surgical pathology, and/or histopathology in order to differentiate between complicated and uncomplicated AA. A new classification of acute appendicitis (CAA) shall be illustrated by typical US and CT images and be employed in a diagnostic and therapeutic algorithm.
methodsMedline, Embase, and the Cochrane Library were searched. Any study after 1970, which investigated clinical scores, pathology, US, CT, magnetic resonance imaging, and treatment of AA, was included. Typical images were taken from the author's image database.
resultsFive main types of AA are defined, normal appendix (type 0), nonvisualised appendix (type X), uncomplicated AA (type 1), complicated AA without perforation (type 2), and complicated AA with perforation (type 3). The imaging modality is indicated by an additional letter, e.g., type p3b for free perforation on pathology. Standardised reporting of the appendix evaluation by US and CT is presented, as well as algorithms for AA management. Imaging features indicating imminent perforation, as well as likely recurrence, were both classified as complicated AA.
conclusionImaging is mandatory in suspected AA. The CAA clearly separates uncomplicated from complicated forms of AA allowing nonoperative management in selected patients with uncomplicated forms of AA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.