Evidence map›Paper›PMID 34142866›Full record

ArticleCannabis and cannabinoid research2021

Diacylglycerol Lipase-β Knockout Mice Display a Sex-Dependent Attenuation of Traumatic Brain Injury-Induced Mortality with No Impact on Memory or Other Functional Consequences.

Lesley D O'Brien, Terry L Smith, Giulia Donvito, Benjamin F Cravatt, Jason Newton, Sarah Spiegel, Thomas M Reeves, Linda L Phillips, Aron H Lichtman

Open access · greenAbstract read
In one paragraph

Article in Cannabis and cannabinoid research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lesley D O'BrienDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
Terry L SmithDepartment of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.
Giulia DonvitoDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
Benjamin F CravattDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.
Jason NewtonDepartment of Biochemistry and Molecular Biology, and Virginia Commonwealth University, Richmond, Virginia, USA.
Sarah SpiegelDepartment of Biochemistry and Molecular Biology, and Virginia Commonwealth University, Richmond, Virginia, USA.
Thomas M ReevesDepartment of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.
Linda L PhillipsDepartment of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.
Aron H LichtmanDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-5601-985X
Virginia Commonwealth University · USScripps Research Institute · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
VCU Center for Drug Addiction ResearchP30DA033934 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew Sean Halquist · 2014 to 2026
$13.8M
SPHINGOSINE AS A MODULATOR OF CELLULAR PROLIFERATIONR01GM043880 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SPIEGEL, SARAH · 1990 to 2023
$3.8M
New approach for cholesterol and sphingolipid reduction in Niemann-Pick C1 diseaseK99HD096117 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEWTON, JASON CHARLES · 2018 to 2019
$248k
High Performance Cryogenic NMR ProbeS10RR015935 · NCRR · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI ZHOU, MING-MING · 2002 to 2002
$207k
NCI NIH HHS P30 CA016059NCRR NIH HHS S10 RR015935NICHD NIH HHS K99 HD096117NIDA NIH HHS P30 DA033934NIGMS NIH HHS R01 GM043880
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain Injuries, TraumaticLipoprotein LipaseAnimalsFemaleMaleMiceMice, KnockoutMicrogliaNeuroinflammatory DiseasesLipoprotein Lipase2-arachidonylglyceroldiacylglycerol lipase-betaendocannabinoidendocannabinoid spatial memorymortalitysphingolipidstraumatic brain injury

Identifiers

PMID34142866
PMCPMC8713276
OpenAlexW3166837907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.