ArticleDevelopment (Cambridge, England)2021
Gene expression variation in Arabidopsis embryos at single-nucleus resolution.
Article in Development (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Single-Nucleus Transcriptome Analysis Provides New Insights Into B Chromosome Elimination in Sorghum.Plant biotechnology journal · 2026Article
- A transcriptional atlas of early Arabidopsis seed development suggests mechanisms for inter-tissue coordination.Nature plants · 2026Article
- Single-cell views of fate reprogramming in de novo organogenesis.Journal of plant research · 2025Review
- Identification of Auxin, Cytokinin, Transcription Factors, and Other Zygotic Embryogenesis-Related Genes inPlants (Basel, Switzerland) · 2025Article
- Dual and spatially resolved drought responses in the Arabidopsis leaf mesophyll revealed by single-cell transcriptomics.The New phytologist · 2025Article
- Investigating biological nitrogen fixation via single-cell transcriptomics.Journal of experimental botany · 2025Review
- ACT2.6: Global Gene Coexpression Network inGenes · 2025Article
- Dissecting the cellular architecture and genetic circuitry of the soybean seed.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Orthologous marker groups reveal broad cell identity conservation across plant single-cell transcriptomes.Nature communications · 2025Article
- Diversity of organ-specific plant transcriptomes.Acta biochimica Polonica · 2025Review
- Best practices for the execution, analysis, and data storage of plant single-cell/nucleus transcriptomics.The Plant cell · 2024Article
- Review
- A Common Molecular Signature Indicates the Pre-Meristematic State of Plant Calli.International journal of molecular sciences · 2023Review
- Multifaceted roles of transcription factors during plant embryogenesis.Frontiers in plant science · 2023Review
- Cell-Type-Specific Profiling of theMembranes · 2022Article
- Review
- Understanding the root xylem plasticity for designing resilient crops.Plant, cell & environment · 2022Review
- Advancing root developmental research through single-cell technologies.Current opinion in plant biology · 2022Review
- Weighted Gene Correlation Network Analysis (WGCNA) ofInternational journal of genomics · 2022Article
- Endosperm-Embryo Communications: Recent Advances and Perspectives.Plants (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Soon after fertilization of egg and sperm, plant genomes become transcriptionally activated and drive a series of coordinated cell divisions to form the basic body plan during embryogenesis. Early embryonic cells rapidly diversify from each other, and investigation of the corresponding gene expression dynamics can help elucidate underlying cellular differentiation programs. However, current plant embryonic transcriptome datasets either lack cell-specific information or have RNA contamination from surrounding non-embryonic tissues. We have coupled fluorescence-activated nuclei sorting together with single-nucleus mRNA-sequencing to construct a gene expression atlas of Arabidopsis thaliana early embryos at single-cell resolution. In addition to characterizing cell-specific transcriptomes, we found evidence that distinct epigenetic and transcriptional regulatory mechanisms operate across emerging embryonic cell types. These datasets and analyses, as well as the approach we devised, are expected to facilitate the discovery of molecular mechanisms underlying pattern formation in plant embryos. This article has an associated 'The people behind the papers' interview.
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Registered trials
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