Evidence map›Paper›PMID 34142653›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2021

Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021.

Finlay Campbell, Brett Archer, Henry Laurenson-Schafer, Yuka Jinnai, Franck Konings, Neale Batra, Boris Pavlin, Katelijn Vandemaele, Maria D Van Kerkhove, Thibaut Jombart and 2 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 516 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
516citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

516 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Integrated framework to study genomic surveillance of selective sweeps in multivariants dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  17. In-hospital mortality among children and adults hospitalized with COVID-19 in Africa across pre-delta, delta, and omicron SARS-CoV-2 waves.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025
    Article
  18. Article
  19. Ulcerative supraglottitis - a unique presentation of COVID-19 infection.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  20. Article

456 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Finlay CampbellHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Brett ArcherHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Henry Laurenson-SchaferHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Yuka JinnaiHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Franck KoningsHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Neale BatraHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Boris PavlinHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Katelijn VandemaeleHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Maria D Van KerkhoveHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Thibaut JombartHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Oliver MorganHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.
Olivier le Polain de WarouxHealth Emergencies Programme, World Health Organization, Geneva, Switzerland.

Funding

Medical Research Council MR/R015600/1World Health Organization 001
6 · The paper itself

Abstract

We present a global analysis of the spread of recently emerged SARS-CoV-2 variants and estimate changes in effective reproduction numbers at country-specific level using sequence data from GISAID. Nearly all investigated countries demonstrated rapid replacement of previously circulating lineages by the World Health Organization-designated variants of concern, with estimated transmissibility increases of 29% (95% CI: 24-33), 25% (95% CI: 20-30), 38% (95% CI: 29-48) and 97% (95% CI: 76-117), respectively, for B.1.1.7, B.1.351, P.1 and B.1.617.2.

Indexed as

COVID-19SARS-CoV-2Basic Reproduction NumberHumansCOVID-19SARS-CoV-2Variants of concernVariants of interest

Identifiers

PMID34142653
PMCPMC8212592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.