Evidence map›Paper›PMID 34142647›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2021

Effectiveness of mRNA COVID-19 vaccines in preventing SARS-CoV-2 infections and COVID-19 hospitalisations and deaths in elderly long-term care facility residents, Spain, weeks 53 2020 to 13 2021.

Clara Mazagatos, Susana Monge, Carmen Olmedo, Lorena Vega, Pilar Gallego, Elisa Martín-Merino, María José Sierra, Aurora Limia, Amparo Larrauri, Working Group for the surveillance and control of COVID-19 in Spain and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The ageing immune system and its battle with viruses.The Journal of general virology · 2026
    Review
  5. Article
  6. [Recommendations on prevention and treatment of respiratory infections in institutionalised older people].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Review
  7. Over- and under-estimation of vaccine effectiveness.BMC medical research methodology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Clara MazagatosNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain, Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Institute of Health Carlos III, Madrid, Spain.
Susana MongeCentre for the Coordination of Alerts and Health Emergencies, General Directorate of Public Health, Ministry of Health, Madrid, Spain.
Carmen OlmedoVaccines Division, General Directorate of Public Health, Ministry of Health, Madrid, Spain.
Lorena VegaNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain, Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Institute of Health Carlos III, Madrid, Spain.
Pilar GallegoNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain, Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Institute of Health Carlos III, Madrid, Spain.
Elisa Martín-MerinoSpanish Agency of Medicines and Medical Devices-AEMPS, Madrid, Spain.
María José SierraCentre for the Coordination of Alerts and Health Emergencies, General Directorate of Public Health, Ministry of Health, Madrid, Spain.
Aurora LimiaVaccines Division, General Directorate of Public Health, Ministry of Health, Madrid, Spain.
Amparo LarrauriNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain, Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Institute of Health Carlos III, Madrid, Spain.
Working Group for the surveillance and control of COVID-19 in SpainMembers are listed under Investigators and at the end of the article.
Working group for the surveillance and control of COVID-19 in Spain
Ministry of Health · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESInstituto de Salud Carlos III · ESAgencia Española de Medicamentos y Productos Sanitarios · ESArtistic Realization Technologies · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Residents in long-term care facilities (LTCF) experienced a large morbidity and mortality during the COVID-19 pandemic in Spain and were prioritised for early COVID-19 vaccination. We used the screening method and population-based data sources to obtain estimates of mRNA COVID-19 vaccine effectiveness for elderly LTCF residents. The estimates were 71% (95% CI: 56-82%), 88% (95% CI: 75-95%), and 97% (95% CI: 92-99%), against SARS-CoV-2 infections (symptomatic and asymptomatic), and COVID-19 hospitalisations and deaths, respectively.

Indexed as

COVID-19COVID-19 VaccinesAgedHospitalizationHumansLong-Term CarePandemicsRNA, MessengerSARS-CoV-2SpainCOVID-19 VaccinesRNA, MessengerCOVID-19LTCFscreeningsurveillancevaccination

Identifiers

PMID34142647
PMCPMC8212595
OpenAlexW3166524079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.