Evidence map›Paper›PMID 34142589›Full record

SynthesisInternational journal of immunopathology and pharmacology

SARS-CoV-2 (COVID-19) and audio-vestibular disorders.

Virginia Fancello, Stavros Hatzopoulos, Virginia Corazzi, Chiara Bianchini, Magdalena B Skarżyńska, Stefano Pelucchi, Piotr Henryk Skarżyński, Andrea Ciorba

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05052320 (Audiological Assessment of Recovered Covid 19 Subjects.), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05052320 unknown statusnot on this map

Audiological Assessment of Recovered Covid 19 Subjects.

Typeobservational_patient_registrySponsorAssiut UniversityRan2021 to 2023Enrolled70ConditionsCovid 19ArmsAudiological assessment
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Hearing loss and COVID-19: an umbrella review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Pooled it
  2. In pursuit of increasing the application of tele-audiology in South Africa: COVID-19 puts on the alert for patient site facilitator training.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Virginia FancelloENT and Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Italy.
Stavros HatzopoulosENT and Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Italy.
Virginia CorazziENT and Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Italy.
Chiara BianchiniENT and Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Italy.
Magdalena B SkarżyńskaInstitute of Sensory Organs, Kajetany, Poland.
Stefano PelucchiENT and Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Italy.
Piotr Henryk SkarżyńskiInstitute of Sensory Organs, Kajetany, Poland.
Andrea CiorbaENT and Audiology Unit, Department of Neuroscience and Rehabilitation, University Hospital of Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0003-3455-2295
University of Ferrara · ITInstitute of Physiology and Pathology of Hearing · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe the audio-vestibular disorders related to the newly SARS-CoV-2 infection, including the possible ototoxicity side-effects related to the use of drugs included in the SARS-CoV-2 treatment protocols. A systematic review was performed according to the PRISMA protocol. The Medline and Embase databases were searched from March 1, 2020 to April 9, 2021. Initially the search yielded 400 manuscripts, which were reduced to 15, upon the application of inclusion criteria. Sensorineural hearing loss (SNHL) is the most frequent audio-vestibular symptom described, occurring alone or in association with tinnitus and vertigo. The etiopathogenesis of the inner ear disorders related to COVID-19 infection is still poorly understood. The number of reports of COVID-19 infections associated to audio-vestibular disorders is increasing; even if the quality of the studies available is often insufficient, audio-vestibular disorders should be considered as possible manifestations to be included among the symptoms of this infection.

Indexed as

COVID-19Hearing Loss, SensorineuralHumansOtotoxicitySARS-CoV-2Vestibular DiseasesCOVID-19hearing lossinner earototoxicitySARS-CoV-2tinnitusvertigo

Identifiers

PMID34142589
PMCPMC8216371
OpenAlexW3166428801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.