Evidence map›Paper›PMID 34142375›Full record

ArticleMagnetic resonance in medicine2021

Characterization and correction of cardiovascular motion artifacts in diffusion-weighted imaging of the pancreas.

Ruiqi Geng, Yuxin Zhang, Jitka Starekova, David R Rutkowski, Lloyd Estkowski, Alejandro Roldán-Alzate, Diego Hernando

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  4. Usefulness of Adaptive Complex Signal Average Diffusion-weighted MR Imaging of the Abdomen.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ruiqi GengDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-5790-5711
Yuxin ZhangDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9852-7959
Jitka StarekovaDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-4285-3090
David R RutkowskiDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-1168-5004
Lloyd EstkowskiGE Healthcare, Waukesha, Wisconsin, USA.
Alejandro Roldán-AlzateDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-4149-4038
Diego HernandoDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-0016-0317
University of Wisconsin–Madison · US

Funding

Quantitative Magnetic Resonance Imaging PhantomsR44EB025729 · NIBIB · CALIMETRIX, LLC · PI BRITTAIN, JEAN H., HERNANDO, DIEGO · 2019 to 2020
$1.5M
Quantitative Magnetic Resonance Imaging PhantomsR41EB025729 · NIBIB · CALIMETRIX, LLC · PI HERNANDO, DIEGO · 2018 to 2018
$239k
Bracco DiagnosticsDepartments of Radiology and Medical Physics, University of Wisconsin-MadisonGE HealthcareNIBIB NIH HHS R41 EB025729NIBIB NIH HHS R41-EB025729NIBIB NIH HHS R44 EB025729NIBIB NIH HHS R44-EB025729Wisconsin Alumni Research Foundation
6 · The paper itself

Abstract

purposeTo assess the effects of cardiovascular-induced motion on conventional DWI of the pancreas and to evaluate motion-robust DWI methods in a motion phantom and healthy volunteers.

methods3T DWI was acquired using standard monopolar and motion-compensated gradient waveforms, including in an anatomically accurate pancreas phantom with controllable compressive motion and healthy volunteers (n = 8, 10). In volunteers, highly controlled single-slice DWI using breath-holding and cardiac gating and whole-pancreas respiratory-triggered DWI were acquired. For each acquisition, the ADC variability across volunteers, as well as ADC differences across parts of the pancreas were evaluated.

resultsIn motion phantom scans, conventional DWI led to biased ADC, whereas motion-compensated waveforms produced consistent ADC. In the breath-held, cardiac-triggered study, conventional DWI led to heterogeneous DW signals and highly variable ADC across the pancreas, whereas motion-compensated DWI avoided these artifacts. In the respiratory-triggered study, conventional DWI produced heterogeneous ADC across the pancreas (head: 1756 ± 173 × 10

conclusionCardiovascular motion introduces artifacts and ADC bias in pancreas DWI, which are addressed by motion-robust DWI.

Indexed as

ArtifactsDiffusion Magnetic Resonance ImagingHumansMotionPancreasReproducibility of Resultscardiovascular compressioncompressive motiondiffusion-weighted imagingDWI artifactspancreas

Identifiers

PMID34142375
PMCPMC8295219
OpenAlexW3167675696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.