Evidence map›Paper›PMID 34142367›Full record

Trial reportBritish journal of haematology2021

Hedgehog blockade in steroid-refractory sclerotic chronic graft-versus-host disease.

Vedran Radojcic, Maria Pletneva, Catherine J Lee, Sanja Ivcevic, Stefanie Sarantopoulos, Daniel Couriel

Abstract readClinical TrialLetter
In one paragraph

Trial report in British journal of haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vedran RadojcicDepartment of Internal Medicine, Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0002-9699-1157
Maria PletnevaDepartment of Pathology, University of Utah, Salt Lake City, UT, USA.
Catherine J LeeDepartment of Internal Medicine, Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT, USA.
Sanja IvcevicHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Stefanie SarantopoulosDepartment of Medicine, Division of Hematologic Malignancies and Cellular Therapy, Duke Cancer Institute, Duke University Medical Center, Durham, England.
Daniel CourielDepartment of Internal Medicine, Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT, USA.

Funding

Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHDR01HL129061 · NHLBI · DUKE UNIVERSITY · PI Stefanie Sarantopoulos · 2015 to 2026
$7.7M
Probing Notch regulation of alloimmunity to uncover novel strategies for graft-versus-host disease controlK08HL145116 · NHLBI · UNIVERSITY OF UTAH · PI RADOJCIC, VEDRAN · 2019 to 2020
$350k
NHLBI NIH HHS K08 HL145116NHLBI NIH HHS R01 HL129061
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralAnilidesBiopsyChronic DiseaseGraft vs Host DiseaseHedgehog ProteinsHematopoietic Stem Cell TransplantationHumansPyridinesSclerosisSkinSteroidsAnilidesHedgehog ProteinsHhAntag691PyridinesSteroids

Identifiers

PMID34142367
PMCPMC8511171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.