Evidence map›Paper›PMID 34142255›Full record

ArticleLasers in medical science2022

Effects of photobiomodulation on bone remodeling in an osteoblast-osteoclast co-culture system.

Ji-Un Hong, Jin-Ju Kwon, Soon Chul Heo, Sang-Hun Shin, Hyung Joon Kim, Jae-Yeol Lee

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ji-Un Hong *Department of Oral and Maxillofacial Surgery, Dental Research Institute, and Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, 50611, Korea.
Jin-Ju Kwon *Department of Oral and Maxillofacial Surgery, Dental Research Institute, and Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, 50611, Korea.
Soon Chul HeoDepartment of Oral Physiology, Periodontal Diseases Signaling Network Research Center, and Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, 50611, Korea.
Sang-Hun ShinDepartment of Oral and Maxillofacial Surgery, Dental Research Institute, and Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, 50611, Korea.
Hyung Joon KimDepartment of Oral Physiology, Periodontal Diseases Signaling Network Research Center, and Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, 50611, Korea. hjoonkim@pusan.ac.kr.ORCID http://orcid.org/0000-0002-2962-9553
Jae-Yeol LeeDepartment of Oral and Maxillofacial Surgery, Dental Research Institute, and Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, 50611, Korea. omsljy@pusan.ac.kr.
Pusan National University · KRPusan National University Dental Hospital · KR

Funding

Pusan National University Dental Hospital PNUDH DRI-2019-02
6 · The paper itself

Abstract

The general bone anabolic effect of photobiomodulation (PBM) is largely accepted. As a result, PBM therapy is expected to be beneficial in the medical fields of dentistry and bone healing. However, most of the previous in vitro studies on PBM and bone metabolism were performed with single-cell cultures of osteoclast-lineage cells or osteoblast-lineage cells. In the present study, the bone-modulating effects of PBM were evaluated in an in vitro osteoblast/osteoclast co-culture system. Mouse bone marrow-derived macrophages (BMMs) and mouse calvarial pre-osteoblasts cells were purified and used as precursor cells for osteoclasts and osteoblasts, respectively. The PBM effects on single-cell culture of osteoclasts or osteoblasts as well as co-culture were examined by 1.2 J/cm

Indexed as

OsteoblastsOsteoclastsAnimalsBone RemodelingCell DifferentiationCoculture TechniquesMiceOsteoprotegerinRANK LigandOsteoprotegerinRANK LigandBone remodelingOsteoblastOsteoclastPhotobiomudulation

Identifiers

PMID34142255
OpenAlexW3172437219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.