ArticleInternational journal of colorectal disease2021
Risk factors for upper and lower type prolonged postoperative ileus following surgery for Crohn's disease.
Article in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Prevalence and risk factors for postoperative ileus in colorectal cancer patients: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease.Nutrients · 2023Pooled it
- Postoperative Ileus After Rectal Cancer Surgery: Assessing Incidence, Severity, and Impact Across Open, Laparoscopic, and Robotic Approaches.Journal of clinical medicine · 2026Article
- Biomarkers and immunomodulatory effect of erythropoietin in postoperative ileus.BMC research notes · 2026Article
- Impact of robotic surgery on postoperative gastrointestinal dysfunction following minimally invasive colorectal surgery: incidence, risk factors, and short-term outcomes.International journal of colorectal disease · 2024Article
- Article
- A critical role for erythropoietin on vagus nerve Schwann cells in intestinal motility.BMC biotechnology · 2023Article
- Factors associated with gastrointestinal dysmotility in critically ill patients.Open medicine (Warsaw, Poland) · 2023Article
- Small intestinal bacterial overgrowth is associated with clinical relapse in patients with quiescent Crohn's disease: a retrospective cohort study.Annals of translational medicine · 2022Article
- A nomogram to predict prolonged postoperative ileus after intestinal resection for Crohn's disease.International journal of colorectal disease · 2022Article
- Interventional inflammatory bowel disease: endoscopic therapy of complications of Crohn's disease.Gastroenterology report · 2022Review
- Article
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Authors and funding
10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeProlonged postoperative ileus (PPOI) is common after bowel resections, especially in Crohn's disease (CD). The pathophysiology of PPOI is not fully understood. PPOI could affect only the upper or lower gastrointestinal (GI) tract. The aim of this study was to assess risk factors for diverse types of PPOI, particularly to differentiate PPOI of upper and lower GI tract.
methodsA retrospective analysis of 163 patients with CD undergoing ileocecal resection from 2015 to 2020 in a single center was performed. PPOI of the upper GI tract was predefined as the presence of vomiting or use of nasogastric tube longer than the third postoperative day. Lower PPOI was predefined as the absence of defecation for more than three days. Independent risk factors were identified by multivariable logistic regression analysis.
resultsOverall incidence of PPOI was 42.7%. PPOI of the upper GI tract was observed in 30.7% and lower PPOI in 20.9% of patients. Independent risk factors for upper PPOI included older age, surgery by a resident surgeon, hand-sewn anastomosis, prolonged opioid analgesia, and reoperation, while for lower PPOI included BMI ≤ 25 kg/m
conclusionThis study identified different risk factors for upper and lower PPOI after ileocecal resection in patients with CD. A differentiated upper/lower type approach should be considered in future research and clinical practice. High-risk patients for each type of PPOI should be closely monitored, and modifiable risk factors, such as preoperative anemia and opioids, should be avoided if possible.
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