Evidence map›Paper›PMID 34142225›Full record

ArticleArchives of gynecology and obstetrics2021

Evaluation of sonographic detectability of different markers within an in vitro simulation model of the axilla.

Selin Guergan, Uta Hoopmann, Carmen Roehm, Bettina Boeer, Regina Fugunt, Gisela Helms, Anna Seller, Mario Marx, Ernst Oberlechner, Andreas Hartkopf and 5 more

Abstract read
In one paragraph

Article in Archives of gynecology and obstetrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Selin GuerganDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Uta HoopmannDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Carmen RoehmDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Bettina BoeerDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Regina FuguntDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Gisela HelmsDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Anna SellerDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Mario MarxDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Ernst OberlechnerDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Andreas HartkopfDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Heike PreibschDiagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany.
Sara BruckerDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Diethelm WallwienerDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Markus HahnDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany.
Ines Verena GruberDepartment for Women's Health, University of Tübingen, Calwerstraße 7, 72076, Tübingen, Germany. ines.gruber@med.uni-tuebingen.de.ORCID 0000-0002-3170-505X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeClip-marking of axillary lymph nodes with initial biopsy-confirmed metastasis is required for targeted axillary dissection (TAD), which includes sentinel lymph node dissection (SLND) and selective localization and removal of the clipped targeted lymph node. There have been several studies which examined the feasibility of TAD in routine clinical use. In this context, the optimal clip visualisation was noted as one of the crucial limiting factors. We, therefore, evaluated the sonographic detectability of 10 different commercially available markers within an in vitro model simulating the anatomical composition of the axilla.

methodsIn this standardised model consisting of porcine fat with 30 mm thickness, the visibility of a total of ten markers was analysed in all 3 planes (parallel, diagonal, orthograde) with wire guidance and then classified into either "visibility good", "visibility moderate" or "visibility poor" with regard to the alignment of the transducer. Additionally, "real-life conditions" were simulated, in which the markers were searched without any wires guidance.

resultsIt was observed that, while not all markers are detectable in fatty tissue, markers with spherical shape (non-embedded Inconel or Nitinol) or rectangular-shaped Titanium markers with embedded material have a clear advantage. 3D-shaped markers can always be detected in all three axes, which is of particular importance in the axilla with its pyramid shape and fatty tissue.

conclusionThe shape and the embedding of the material play a crucial role for visibility and efficacy of the marker, as reliable marking of suspicious and pathological axillary lymph nodes is essential for TAD.

Indexed as

Sentinel Lymph NodeAnimalsAxillaBreast NeoplasmsFemaleHumansLymphatic MetastasisLymph Node ExcisionLymph NodesMastectomyNeoplasm StagingSentinel Lymph Node BiopsyBreast cancerClip-markingLymph nodeSonographic detectabilityTargeted axillary dissection

Identifiers

PMID34142225
PMCPMC8325667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.