Evidence map›Paper›PMID 34142088›Full record

ArticleRadiology. Artificial intelligence2021

Automatic Deep Learning-assisted Detection and Grading of Abnormalities in Knee MRI Studies.

Bruno Astuto, Io Flament, Nikan K Namiri, Rutwik Shah, Upasana Bharadwaj, Thomas M Link, Matthew D Bucknor, Valentina Pedoia, Sharmila Majumdar

Erratum issuedAbstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 68 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Bruno AstutoCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0002-8890-7963
Io FlamentCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0001-6396-6417
Nikan K NamiriCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0003-2943-9546
Rutwik ShahCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0002-4290-1320
Upasana BharadwajCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.
Thomas M LinkCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0002-2850-8143
Matthew D BucknorCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0001-6082-515X
Valentina PedoiaCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0002-9745-955X
Sharmila MajumdarCenter for Intelligent Imaging and Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging (B.A., I.F., N.K.N., R.S., U.B., T.M.L., M.D.B., V.P., S.M.), and Center of Digital Health Innovation (V.P., S.M.), University of California-San Francisco, 1700 Fourth St, Suite 201, QB3 Building, San Francisco, CA 94107.ORCID https://orcid.org/0000-0002-0201-871X

Funding

MRI TO STUDY CARTILAGE/BONE INTERACTIONSR01AR046905 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA · 1999 to 2015
$6.3M
Translation of Quantitative Imaging in OsteoarthritisP50AR060752 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2015
$6.2M
Deep Learning for Characterizing Knee Joint Degeneration Predicting Progression of Osteoarthritis and Total Knee ReplacementR61AR073552 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA, PEDOIA, VALENTINA · 2018 to 2019
$871k
Multidimensional MRI-based Non-Euclidean Deep Learning to Study OsteoarthritisR00AR070902 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PEDOIA, VALENTINA · 2018 to 2020
$747k
NIAMS NIH HHS P50 AR060752NIAMS NIH HHS R00 AR070902NIAMS NIH HHS R01 AR046905NIAMS NIH HHS R61 AR073552
6 · The paper itself

Abstract

purposeTo test the hypothesis that artificial intelligence (AI) techniques can aid in identifying and assessing lesion severity in the cartilage, bone marrow, meniscus, and anterior cruciate ligament (ACL) in the knee, improving overall MRI interreader agreement. MATERIALS AND

methodsThis retrospective study was conducted on 1435 knee MRI studies (

resultsBinary lesion sensitivity reported for all tissues was between 70% and 88%. Specificity ranged from 85% to 89%. The area under the receiver operating characteristic curve for all tissues ranged from 0.83 to 0.93. Deep learning-assisted intergrader Cohen ĸ agreement significantly improved in 10 of 16 comparisons among two attending physicians and two trainees for all tissues.

conclusionThe three-dimensional convolutional neural network had high sensitivity, specificity, and accuracy for knee-lesion-severity scoring and also increased intergrader agreement when used on an external dataset.

Identifiers

PMID34142088
PMCPMC8166108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.