Evidence map›Paper›PMID 34141763›Full record

ArticleWorld journal of clinical cases2021

Transient immune hepatitis as post-coronavirus disease complication: A case report.

Anca Cristina Drăgănescu, Oana Săndulescu, Anuța Bilașco, Camelia Kouris, Anca Streinu-Cercel, Monica Luminos, Adrian Streinu-Cercel

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. COVID-19-Associated Liver Injury.Hepatic medicine : evidence and research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anca Cristina DrăgănescuInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Oana SăndulescuInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Anuța BilașcoInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Camelia KourisInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Anca Streinu-CercelInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Monica LuminosInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Adrian Streinu-CercelInfectious Diseases Department, National Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest 021105, Romania.
Infectious Diseases Institute · UG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe report a case of post-coronavirus disease (COVID) immune hepatitis occurring in a young male with no pre-existing comorbidities. CASE SUMMARY: A previously healthy 21-year-old male patient was admitted to our hospital with mild COVID-19. During the course of in-hospital isolation and monitoring, he developed an alanine aminotransferase (ALT) and aspartate aminotransferase (AST) increase, with the enzymes peaking at day 24 (ALT 15 times the upper normal limit), with preserved liver function. The liver enzyme increase occurred 20 d after the complete clinical remission of COVID-19, and ALT dynamics paralleled the increase in total antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The case was interpreted as post-COVID immune hepatitis, with extensive laboratory investigations excluding other potential causes. The hepatocytolysis remitted 20 d after the peak ALT, without further intervention, with complete recovery, but the total anti-SARS-CoV-2 antibodies continued to increase the next 5 mo following the acute infection.

conclusionClose attention should also be paid to young patients with mild forms of disease, and a high index of suspicion should be maintained for post-COVID complications.

Indexed as

Case reportComplicationsCOVID-19Liver

Identifiers

PMID34141763
PMCPMC8180208
OpenAlexW3160055384

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.