Evidence map›Paper›PMID 34141617›Full record

ArticleFrontiers in oncology2021

Regulatory Mechanisms and Functional Roles of Hypoxia-Induced Long Non-Coding RNA

Yi-Chun Cheng, Li-Yu Su, Li-Han Chen, Tzu-Pin Lu, Eric Y Chuang, Mong-Hsun Tsai, Li-Ling Chuang, Liang-Chuan Lai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Mitochondrial epigenetic mechanisms in cancer: an updated overview.Frontiers in cell and developmental biology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Hypoxia-driven ncRNAs in breast cancer.Frontiers in oncology · 2023
    Review
  8. Changes in Mitochondrial Epigenome in Type 2 Diabetes Mellitus.British journal of biomedical science · 2023
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yi-Chun ChengInstitute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Li-Yu SuInstitute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Li-Han ChenInstitute of Fisheries Science, College of Life Science, National Taiwan University, Taipei, Taiwan.
Tzu-Pin LuInstitute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan.
Eric Y ChuangBioinformatics and Biostatistics Core, Center of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.
Mong-Hsun TsaiBioinformatics and Biostatistics Core, Center of Genomic and Precision Medicine, National Taiwan University, Taipei, Taiwan.
Li-Ling ChuangSchool of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Liang-Chuan LaiInstitute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TWChang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been found to participate in multiple genetic pathways in cancer. Also, mitochondria-associated lncRNAs have been discovered to modulate mitochondrial function and metabolism. Previously, we identified oxygen-responsive lncRNAs in MCF-7 breast cancer cells under different oxygen concentrations. Among them, a novel mitochondria-encoded lncRNA,

Indexed as

breast cancerfunctionhypoxialong noncoding RNAmicroRNAmitochondria

Identifiers

PMID34141617
PMCPMC8204045
OpenAlexW3171857691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.