Evidence map›Paper›PMID 34141563›Full record

ArticleLeukemia research reports2021

Acute myeloid leukemia with hepatic infiltration presenting as obstructive jaundice.

Landis R Walsh, Chaofan Yuan, James T Boothe, Heather E Conway, Andres E Mindiola-Romero, Odeth O Barrett-Campbell, Swaroopa Yerrabothala, Frederick Lansigan

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Leukemia research reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Gut and liver involvement in pediatric hematolymphoid malignancies.World journal of gastrointestinal oncology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Landis R WalshGeisel School of Medicine at Dartmouth, Hanover, NH, USA.
Chaofan YuanDepartment of Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH USA.
James T BootheDepartment of Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH USA.
Heather E ConwayDepartment of Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH USA.
Andres E Mindiola-RomeroDepartment of Pathology & Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH USA.
Odeth O Barrett-CampbellGeisel School of Medicine at Dartmouth, Hanover, NH, USA.
Swaroopa YerrabothalaGeisel School of Medicine at Dartmouth, Hanover, NH, USA.
Frederick LansiganGeisel School of Medicine at Dartmouth, Hanover, NH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 55-year-old woman who presented with laboratory studies concerning for acute myeloid leukemia (AML) as well as obstructive cholestasis. In similar previously reported cases, concerns of chemotherapy toxicity exacerbated by liver dysfunction or concerns of untreated, concurrent cholecystitis in a neutropenic patient often delay initiation of chemotherapy for full medical workup. At admission, our patient was started on the cytoreductive agent hydroxyurea. By day 10 of her medical workup, her liver function had improved with total bilirubin levels normalizing. At that time, full-dose 7 + 3 induction with cytarabine and daunorubicin was then initiated.

Indexed as

Acute myeloid leukemiaChemotherapyCytoreductive therapyExtramedullary manifestation of AMLHydroxyurea

Identifiers

PMID34141563
PMCPMC8184649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.