ReviewAnnals of medicine and surgery (2012)2021
Methanol poisoning as a new world challenge: A review.
Review in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.
- Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Pooled it
- Diagnostic Challenges of Methanol Poisoning in Resource-Limited Settings: A Case Series.Clinical case reports · 2026Article
- Predictors of in-hospital mortality: after a methanol poisoning outbreak in Istanbul.BMC emergency medicine · 2026Observational
- Rapid on-site methanol screening in distilled spirits via BME688 MOX sensor array and machine learning.Scientific reports · 2026Article
- Article
- Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame.Allergy · 2026Article
- Postmortem Methanol and Formic Acid Levels and Their Pathological Correlates: Diagnostic Implications from an Autopsy Study.Diagnostics (Basel, Switzerland) · 2026Article
- Alcohol consumption "fuels" dimethyl sulfate vapor poisoning: a case report of three patients.AME case reports · 2026Article
- Oxidative stress mechanisms and potential biomarkers of methyl acetate poisoning: a urinary metabolomics study in rat model and human occupational cohort.Frontiers in molecular biosciences · 2026Article
- Occult cerebral hemorrhage induced by high-dose oral methanol poisoning: a case report.Frontiers in pharmacology · 2026Article
- Alcohol poisoning, in the shadow of a COVID-19 pandemic: a 5-year review of methanol/ethanol toxicity in Northern Iran.BMC emergency medicine · 2025Article
- Methanol poisoning in the emergency department: methanol blood levels, prognosis, and sequelae outcomes.Irish journal of medical science · 2025Article
- Methanol Poisoning Without Typical Diagnostic Clues or Standard Antidotes: A Case Report on Clinical Decision-Making.Cureus · 2025Article
- Antioxidant and Photoprotective Activities ofAntioxidants (Basel, Switzerland) · 2025Article
- Influence of Jackfruit Wood Barrels and Chips During Aging on the Quality and Phenolic Compounds of Cachaça.Foods (Basel, Switzerland) · 2025Article
- Alcohol as poison: a narrative review of social science scholarship relevant to methanol poisoning in low- and middle-income countries.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Review
- Low-Cost Raman Spectroscopy Setup Combined with a Machine Learning Model.Sensors (Basel, Switzerland) · 2025Article
- Prognostic role of the systemic immune-inflammation index and pan-immune-inflammation value in acute methanol poisoning.Turkish journal of medical sciences · 2025Article
- Concurrent Hyperparathyroidism and Wilson's Disease in a Patient With Methanol Toxicity: A Rare Case Report.Clinical medicine insights. Endocrinology and diabetes · 2025Article
- Toxicity of formaldehyde, and its role in the formation of harmful and aromatic compounds during food processing.Food chemistry: X · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMethanol poisoning (MP) occurs often via ingestion, inhalation, or dermal exposure to formulations containing methanol in base. Clinical manifestations of MP include gastrointestinal symptoms, central nervous system (CNS) suppression, and decompensated metabolic acidosis occurred with blurred vision and early or late blindness.
objectiveThis study reviewed the clinical manifestations, laboratory and radiology findings, and treatment approaches in MP. DISCUSSION: Methanol is usually rapidly absorbed after ingestion and metabolized by alcohol dehydrogenase (ADH), then distributed to the body water to reach a volume distribution approximately equal to 0.77 L/kg. It is also eliminated from the body as unchanged parent compounds. Clinical manifestations of MP alone initiate within 0.5-4 h after ingestion and include gastrointestinal symptoms and CNS suppression. After a latent period of 6-24 h, depending on the absorbed dose, decompensated metabolic acidosis occurs with blurred vision and early or late blindness. Blurred vision with normal consciousness is a strong suspicious sign of an MP. The mortality and severity of intoxication are well associated with the severity of CNS depression, hyperglycemia, and metabolic acidosis, but not with serum methanol concentration. After initial resuscitation, the most important therapeutic action for patients with known or suspected MP is correction of acidosis, inhibition of ADH, and hemodialysis.
conclusionSince MP is associated with high morbidity and mortality, it should be considered seriously and instantly managed. Delay in treatment may cause complications, permanent damage, and even death.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.