ArticleClinical kidney journal2021
Optimization of dialysate bicarbonate in patients treated with online haemodiafiltration.
Article in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Article
- Concurrent Control of Sodium and Bicarbonate Serum Concentrations Using a Four-Stream Hemodialysis Fluid Delivery System.Hemodialysis international. International Symposium on Home Hemodialysis · 2025Article
- Development and validation of an algorithm for identifying patients undergoing dialysis from patients with advanced chronic kidney disease.Clinical and experimental nephrology · 2025Article
- The Effect of Dialysate Bicarbonate Concentration or Oral Bicarbonate Supplementation on Outcomes in Patients on Maintenance Dialysis: A Systematic Review and Meta-Analysis.Canadian journal of kidney health and disease · 2025Article
- Association Between the Dialysate Bicarbonate and the Pre-dialysis Serum Bicarbonate Concentration in Maintenance Hemodialysis: A Retrospective Cohort Study.Canadian journal of kidney health and disease · 2024Article
- The role of intra- and interdialytic sodium balance and restriction in dialysis therapies.Frontiers in medicine · 2023Review
- Acid-base balance in hemodialysis patients in everyday practice.Renal failure · 2022Article
- Tailoring the dialysate bicarbonate eliminates pre-dialysis acidosis and post-dialysis alkalosis.Clinical kidney journal · 2022Article
- High volume online hemodiafiltration: a global perspective and the Brazilian experience.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic acidosis is a common problem in haemodialysis patients, but acidosis overcorrection has been associated with higher mortality. There is no clear definition of the optimal serum bicarbonate target or dialysate bicarbonate. This study analysed the impact of reducing dialysate bicarbonate from 35 to 32 mEq/L on plasma bicarbonate levels in a cohort of patients treated with online haemodiafiltration (OL-HDF).
methodsWe performed a prospective cohort study with patients in a stable chronic OL-HDF programme for at least 12 months in the Hospital Clinic of Barcelona. We analysed pre- and post-dialysis total carbon dioxide(TCO
resultsWe included 84 patients with a 6-month follow-up. At 6 months, pre- and post-dialysis TCO
conclusionsReducing dialysate bicarbonate concentration by 3 mEq/L significantly and safely decreased pre- and post-dialysis TCO
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Registered trials
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