Evidence map›Paper›PMID 34141169›Full record

ArticleToxicology research2021

Galangin attenuates oxidative stress-mediated apoptosis in high glucose-induced renal tubular epithelial cells through modulating renin-angiotensin system and PI3K/AKT/mTOR pathway.

Jie Liao, Bo Liu, Ke Chen, Sheng Hu, Zheng-Yu Liu, Yu-Xin Li, Zhi-Ming Yang, Meng Zhang, Xiong Chen

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Histology and histopathology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Programmed Cell Death in Diabetic Nephropathy: A Review of Apoptosis, Autophagy, and Necroptosis.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jie LiaoDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Bo LiuDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Ke ChenDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Sheng HuDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Zheng-Yu LiuDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Yu-Xin LiDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Zhi-Ming YangInternational Medical Center, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Meng ZhangDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Xiong ChenDepartment of Geriatric Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, P.R. China.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was to evaluate the regulatory network among Galangin (Gal), oxidative stress, and renin-angiotensin system (RAS) in diabetic nephropathy (DN)

Indexed as

diabetic nephropathyGalanginoxidative stressPI3K/AKT/mTOR signalrenin–angiotensin system

Identifiers

PMID34141169
PMCPMC8201591
OpenAlexW3161486872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.