Evidence map›Paper›PMID 34141167›Full record

ArticleToxicology research2021

Ganoderic acid T improves the radiosensitivity of HeLa cells via converting apoptosis to necroptosis.

Chang-Sheng Shao, Na Feng, Shuai Zhou, Xin-Xin Zheng, Peng Wang, Jing-Song Zhang, Qing Huang

Open access · bronzeAbstract read
In one paragraph

Article in Toxicology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. CanPharmaceuticals (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Necroptosis: A Pathogenic Negotiator in Human Diseases.International journal of molecular sciences · 2022
    Review
  9. Article
  10. American journal of cancer research · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chang-Sheng ShaoCAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei 230031, China.
Na FengKey Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P. R., China.
Shuai ZhouKey Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P. R., China.
Xin-Xin ZhengCAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei 230031, China.
Peng WangCAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei 230031, China.
Jing-Song ZhangKey Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P. R., China.
Qing HuangCAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei 230031, China.
Chinese Academy of Sciences · CNShanghai Academy of Agricultural Sciences · CNHefei Institutes of Physical Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of natural substances derived from traditional Chinese medicine and natural plants as safe radiosensitizing adjuvants is a new trend for cancer radiotherapy.

Indexed as

apoptosisganoderic acid T (GAT)ionizing radiationnecroptosisradiosensitivitytriterpene

Identifiers

PMID34141167
PMCPMC8201584
OpenAlexW3160120346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.