Evidence map›Paper›PMID 34141083›Full record

ArticleACS medicinal chemistry letters2021

Structure-Activity Relationship for the Picolinamide Antibacterials that Selectively Target

Enrico Speri, Yuanyuan Qian, Jeshina Janardhanan, Cesar Masitas, Elena Lastochkin, Stefania De Benedetti, Man Wang, Valerie A Schroeder, William R Wolter, Allen G Oliver and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Enrico SperiDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Yuanyuan QianDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Jeshina JanardhananDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Cesar MasitasDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Elena LastochkinDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Stefania De BenedettiDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Man WangDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Valerie A SchroederDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
William R WolterFreimann Life Sciences Center, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Allen G OliverDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Jed F FisherDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
Shahriar MobasheryDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0002-7695-7883
Mayland ChangDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.ORCID 0000-0002-4333-3775
University of Notre Dame · US

Funding

Inducible Antibiotic Resistance in Methicillin-Resistant Staphylococcus AureusR01AI104987 · NIAID · UNIVERSITY OF NOTRE DAME · PI Shahriar Mobashery · 2013 to 2026
$7.3M
Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
The quinazolinone class of antibacterial agentsR01AI116548 · NIAID · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F · 2015 to 2019
$3.0M
NIAID NIH HHS R01 AI104987NIAID NIH HHS R01 AI116548NIGMS NIH HHS T32 GM075762
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID34141083
PMCPMC8201750
OpenAlexW3158556298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.