Evidence map›Paper›PMID 34141051›Full record

ArticleThe World Allergy Organization journal2021

Impact of COVID-19 pandemic on asthma symptoms and management: A prospective analysis of asthmatic children in Ecuador.

Angélica M Ochoa-Avilés, Cristina Ochoa-Avilés, Diana A Morillo-Argudo, María José Molina-Cando, Claudia R Rodas-Espinoza, Irina Chis Ster, Manolo P Maestre Calderón, Augusto Maldonado G, Karen Arteaga Vaca, Alejandro Rodriguez and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The World Allergy Organization journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. COVID-19 in a group of children with asthma: presentation, severity, and outcome.American journal of clinical and experimental immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Angélica M Ochoa-AvilésDepartment of Biosciences, Faculty of Chemistry, University of Cuenca, Cuenca, Azuay, Ecuador.
Cristina Ochoa-AvilésDepartment of Biosciences, Faculty of Chemistry, University of Cuenca, Cuenca, Azuay, Ecuador.
Diana A Morillo-ArgudoSchool of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador.
María José Molina-CandoDepartment of Biosciences, Faculty of Chemistry, University of Cuenca, Cuenca, Azuay, Ecuador.
Claudia R Rodas-EspinozaFaculty of Medicine, University of Azuay, Cuenca, Azuay, Ecuador.
Irina Chis SterInstitute of Infection and Immunity, St George's University of London, London, UK.
Manolo P Maestre CalderónDepartment of Pediatrics Hospital Vicente Corral Moscoso, Cuenca, Azuay, Ecuador.
Augusto Maldonado GUniversidad San Francisco de Quito School of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hospital General Docente de Calderón, Quito, Pichincha, Ecuador.
Karen Arteaga VacaHospital Regional Verdi Cevallos, Portoviejo, Manabí, Ecuador.
Alejandro RodriguezSchool of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador.
Alvaro A CruzFundação ProAR and Universidade Federal da Bahia, Salvador, Brazil.
Natalia Romero-SandovalSchool of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador.
Philip J CooperSchool of Medicine, International University of Ecuador, Quito, Pichincha, Ecuador.
Universidad Internacional del Ecuador · ECSt George's, University of London · GBUniversidade Federal da Bahia · BRUniversity of Cuenca · ECHospital General Docente de CalderónHospital Vicente Corral Moscoso · ECUniversidad del Azuay · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma affects up to 33% of children in Latin American settings. The ongoing COVID-19 pandemic has had a significant impact on access to and use of health services. We aimed to evaluate the impact of the COVID-19 lockdown on asthma exacerbations, medical facility visits, and use of asthma medications in children.

methodsWe used data from a prospective cohort of 213 children aged 5-17 years in 3 Ecuadorian cities and analysed the impact of the COVID-19 lockdown on asthma. Outcomes (asthma exacerbations, emergency room [ER] visits, planned and unplanned outpatient visits, and use of inhaled corticosteroids and Beta-2 agonists) were analysed using repeated Poisson counts (ie, number of events per participant before and during the COVID-19 lockdown).

resultsDuring compared to before lockdown: a) the number of asthma exacerbations remained constant (IRR, 0.87; 95% CI: 0.72-1.05; p = 0.152); b) outpatient visits (IRR 0.26, 95% CI 0.14-0.47, p < 0.001) declined 74% while ER visits declined 89% (IRR 0.11, 95% CI 0.04-0.32, p < 0.001); and c) there was no change in inhaled corticosteroids use (IRR 1.03, 95% CI 0.90-1.16, P = 0.699) while Beta-2 agonist use increased (IRR 1.32, 95% CI 1.10-1.58, P = 0.003).

conclusionsIn a cohort of Ecuadorian children with asthma, health services attendance decreased dramatically after COVID-19 lockdown, but asthma exacerbations and use of inhaled corticosteroids were unchanged. Future analyses will address the question of the effect of SARS-CoV-2 infection on asthma exacerbations and control in this paediatric population.

Indexed as

AsthmaChildrenCOVID-19EcuadorLockdown

Identifiers

PMID34141051
PMCPMC8190468
OpenAlexW3166801132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.