Evidence map›Paper›PMID 34141015›Full record

ArticleJournal of arrhythmia2021

Efficacy and safety of the second-generation cryoballoon ablation for the treatment of persistent atrial fibrillation in elderly patients.

Gaëlle Vermeersch, Juan-Pablo Abugattas, Varnavas Varnavas, Jeroen De Cocker, Bruno Schwagten, Juan Sieira, Carlo de Asmundis, Gian-Battista Chierchia, Yves De Greef

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Clinical outcomes after catheter ablation for atrial fibrillation in elderly patients: a meta-analysis with time-to-event data reconstruction.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
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  7. Cryoballoon ablation of atrial fibrillation in octogenarians: one year outcomes from the cryo global registry.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  8. Predictors of outcome after catheter ablation for atrial fibrillation: Group analysis categorized by age and type of atrial fibrillation.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Article
  9. Atrial Fibrillation: Rate Versus Rhythm Control.HCA healthcare journal of medicine · 2023
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Gaëlle VermeerschElectrophysiology Unit ZNA Heart Centre Middelheim Antwerpen Belgium.ORCID https://orcid.org/0000-0001-9124-7188
Juan-Pablo AbugattasElectrophysiology Unit ZNA Heart Centre Middelheim Antwerpen Belgium.ORCID https://orcid.org/0000-0003-3960-770X
Varnavas VarnavasElectrophysiology Unit ZNA Heart Centre Middelheim Antwerpen Belgium.ORCID https://orcid.org/0000-0001-9715-1611
Jeroen De CockerElectrophysiology Unit ZNA Heart Centre Middelheim Antwerpen Belgium.
Bruno SchwagtenElectrophysiology Unit ZNA Heart Centre Middelheim Antwerpen Belgium.
Juan SieiraHeart Rhythm Management Centre Universitair Ziekenhuis Brussel Vrije Universiteit Brussel Brussels Belgium.ORCID https://orcid.org/0000-0002-8865-2120
Carlo de AsmundisHeart Rhythm Management Centre Universitair Ziekenhuis Brussel Vrije Universiteit Brussel Brussels Belgium.ORCID https://orcid.org/0000-0001-9351-0760
Gian-Battista ChierchiaHeart Rhythm Management Centre Universitair Ziekenhuis Brussel Vrije Universiteit Brussel Brussels Belgium.ORCID https://orcid.org/0000-0003-2967-1345
Yves De GreefElectrophysiology Unit ZNA Heart Centre Middelheim Antwerpen Belgium.ORCID https://orcid.org/0000-0003-1367-4867
Vrije Universiteit Brussel · BEZNA Middelheim Hospital · BEUniversité Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is expected that ablation procedures will be increasingly offered to a more aged population affected with persistent AF (persAF); however, the clinical outcomes of ablation in this specific population are not well described. We aimed to analyze the efficacy and safety of CB-A in this group of patients compared with a younger cohort. METHODS AND

resultsEighty-three patients with (persAF) aged ≥75 years (group 1; mean age 78.2 ± 3.1 years) and 166 patients also affected with persAF aged <75 years (group 2; mean age 64.3 ± 6.6 years) were included in the study. The primary outcome was freedom from recurrent sustained (>30 seconds) atrial arrhythmias without anti-arrhythmic medication after a blanking period of 3 months. At 2 years, clinical success was achieved in 108 out of 249 patients (43.4%). Median follow-up was 24 months (IQR: 18.4-25.5 months). Older patients suffered from more recurrences than those in the younger cohort ((53/83 patients, 63.9% vs 88/166 patients, 53.0%;

conclusionsThe global 2 years efficacy of CB-A PVI in persAF is 43.4%. A lower success rate is achieved in the older patients (36.1%) compared to the younger age group (47.0%). However, the complication rate was not different between age groups.

Identifiers

PMID34141015
PMCPMC8207396
OpenAlexW3149560166

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.