Evidence map›Paper›PMID 34141008›Full record

ArticleJournal of arrhythmia2021

Optimized lesion size index (o-LSI): A novel predictor for sufficient ablation of pulmonary vein isolation.

Gen Matsuura, Jun Kishihara, Hidehira Fukaya, Jun Oikawa, Naruya Ishizue, Daiki Saito, Tetsuro Sato, Yuki Arakawa, Shuhei Kobayashi, Yuki Shirakawa and 4 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Lesion size indices for cavotricuspid isthmus ablation: superior or superfluous?Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gen MatsuuraDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.ORCID https://orcid.org/0000-0003-0165-5677
Jun KishiharaDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.ORCID https://orcid.org/0000-0002-5920-4417
Hidehira FukayaDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.ORCID https://orcid.org/0000-0002-7588-554X
Jun OikawaDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Naruya IshizueDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Daiki SaitoDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Tetsuro SatoDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Yuki ArakawaDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Shuhei KobayashiDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Yuki ShirakawaDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Ryo NishinaritaDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.ORCID https://orcid.org/0000-0003-0329-5476
Ai HoriguchiDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Shinichi NiwanoDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.ORCID https://orcid.org/0000-0002-0702-0800
Junya AkoDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the lesion size index (LSI) has been well established, it is sometimes difficult to achieve first-pass pulmonary vein isolation (PVI) and to avoid acute pulmonary vein reconnections, even with LSI-guided procedures. The purpose of this study was to assess the predictive accuracy of a novel parameter, the optimized lesion size index (o-LSI), to perform PVI.

methodsThe voltage maps created by the Advisor™ high-density (HD) grid catheter before PVI in 35 atrial fibrillation (AF) patients were examined for an association between the voltage amplitude and insufficient ablation sites (IAS), which were defined as either (i) spontaneous reconnection sites, (ii) dormant PV conduction sites unmasked with 20 mg of adenosine triphosphate disodium hydrate (ATP) injection, or (iii) PV-LA gap sites after the initial PVI.

resultsIAS was observed in 25/1417 of the total ablation sites. IAS was significantly associated with higher bipolar voltage areas (4.20 ± 2.68 vs 2.43 ± 1.93 mV,

conclusionLow o-LSI was strongly associated with IAS, potentially providing a novel index to improve first-pass PV isolation.

Indexed as

atrial fibrillationhigh‐voltage zoneinsufficient ablation siteslesion size indexpulmonary vein isolation

Identifiers

PMID34141008
PMCPMC8207405

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.