Evidence map›Paper›PMID 34140969›Full record

ArticleFrontiers in genetics2021

Genome-Wide Variants Associated With Longitudinal Survival Outcomes Among Individuals With Coronary Artery Disease.

Jennifer R Dungan, Xue Qin, Melissa Hurdle, Carol S Haynes, Elizabeth R Hauser, William E Kraus

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Research summary of poster presentations at the 2023 Florida cardio-oncology symposium.American heart journal plus : cardiology research and practice · 2024
    Article
  6. Article
  7. Sex-dimorphic gene effects on survival outcomes in people with coronary artery disease.American heart journal plus : cardiology research and practice · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jennifer R DunganDivision of Healthcare in Adult Populations, School of Nursing, Duke University, Durham, NC, United States.
Xue QinSchool of Medicine, Duke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Melissa HurdleSchool of Medicine, Duke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Carol S HaynesSchool of Medicine, Duke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Elizabeth R HauserSchool of Medicine, Duke Molecular Physiology Institute, Duke University, Durham, NC, United States.
William E KrausSchool of Medicine, Duke Molecular Physiology Institute, Duke University, Durham, NC, United States.
Duke University · USDurham VA Medical Center · US

Funding

BEHAVIOR AND PHYSIOLOGY IN AGINGT32AG000029 · NIA · DUKE UNIVERSITY · PI Maria Marquine · 1985 to 2026
$9.3M
Metabolomic Quantitative Trait Locus (mQTL) Genetic Mapping in Human CVDR01HL095987 · NHLBI · DUKE UNIVERSITY · PI SHAH, SVATI H. · 2009 to 2013
$3.4M
Genetic Mediators of Metabolic Cardiovascular Disease RiskRC2HL101621 · NHLBI · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 2009 to 2010
$3.2M
Expanding Evidence of Genetic Contributions to Survivorship in CADR00NR011054 · NINR · DUKE UNIVERSITY · PI DUNGAN, JENNIFER R · 2011 to 2013
$725k
Survival and Age Biases in Gene Associations with Coronary DiseaseK99NR011054 · NINR · DUKE UNIVERSITY · PI DUNGAN, JENNIFER R · 2009 to 2010
$172k
NHLBI NIH HHS R01 HL095987NHLBI NIH HHS RC2 HL101621NIA NIH HHS T32 AG000029NINR NIH HHS K99 NR011054NINR NIH HHS R00 NR011054
6 · The paper itself

Abstract

objectiveCoronary artery disease (CAD) is an age-associated condition that greatly increases the risk of mortality. The purpose of this study was to identify gene variants associated with all-cause mortality among individuals with clinically phenotyped CAD using a genome-wide screening approach. APPROACH AND

resultsWe performed discovery (

conclusionReplicated findings identified two candidate genes for further study regarding association with survival in high-risk CAD patients: novel loci

Indexed as

age-related diseasecandidate gene analysescoronary artery diseasegenome-wide association studysurvival analysis

Identifiers

PMID34140969
PMCPMC8204081
OpenAlexW3167121795

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.