Evidence map›Paper›PMID 34140948›Full record

ArticleFrontiers in immunology2021

Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population.

Sayaka Ishihara, Tsuyoshi Sato, Risa Sugioka, Ryota Miwa, Haruka Saito, Ryota Sato, Hidehiro Fukuyama, Akihiko Nakajima, Satoshi Sawai, Ai Kotani and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sayaka IshiharaDepartment of Biosciences, School of Science, Kitasato University, Sagamihara, Japan.
Tsuyoshi SatoDepartment of Biosciences, School of Science, Kitasato University, Sagamihara, Japan.
Risa SugiokaDepartment of Biosciences, School of Science, Kitasato University, Sagamihara, Japan.
Ryota MiwaDepartment of Biosciences, School of Science, Kitasato University, Sagamihara, Japan.
Haruka SaitoDepartment of Biosciences, School of Science, Kitasato University, Sagamihara, Japan.
Ryota SatoLaboratory of Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Hidehiro FukuyamaLaboratory of Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Akihiko NakajimaDepartment of Basic Science, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, Japan.
Satoshi SawaiDepartment of Basic Science, Graduate School of Arts and Sciences, University of Tokyo, Tokyo, Japan.
Ai KotaniDepartment of Hematological Malignancy, Institute of Medical Science, Tokai University, Isehara, Japan.
Koko KatagiriDepartment of Biosciences, School of Science, Kitasato University, Sagamihara, Japan.
Kitasato University · JPRIKEN Center for Integrative Medical Sciences · JPThe University of Tokyo · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrin regulation by Rap1 is indispensable for lymphocyte recirculation. In mice having B-cell-specific

Indexed as

Chemotaxis, LeukocyteAnimalsB-LymphocytesChemokine CXCL12gamma-GlobulinsGerminal CenterImmunity, HumoralImmunizationIntercellular Adhesion Molecule-1LiverMiceMice, Inbred C57BLMice, KnockoutPrecursor Cells, B-Lymphoidrap1 GTP-Binding Proteinsrap GTP-Binding ProteinsChemokine CXCL12Cxcl12 protein, mousedinitrophenyl gamma globulingamma-GlobulinsIcam1 protein, mouseIntercellular Adhesion Molecule-1rap1A protein, mouseRap1b protein, mouserap1 GTP-Binding Proteinsrap GTP-Binding ProteinsVascular Cell Adhesion Molecule-1B-1aB cellschemotactic factorgerminal centerRap1

Identifiers

PMID34140948
PMCPMC8203927
OpenAlexW3170995434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.