Evidence map›Paper›PMID 34140944›Full record

ArticleFrontiers in microbiology2021

Nasal and Fecal Microbiota and Immunoprofiling of Infants With and Without RSV Bronchiolitis.

Claudio Alba, Marina Aparicio, Felipe González-Martínez, María Isabel González-Sánchez, Jimena Pérez-Moreno, Blanca Toledo Del Castillo, Juan Miguel Rodríguez, Rosa Rodríguez-Fernández, Leonides Fernández

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  4. bioRxiv : the preprint server for biology · 2026
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  17. Administration ofFrontiers in microbiology · 2022
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  19. Administration ofFoods (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Claudio AlbaDepartment of Nutrition and Food Science, Complutense University of Madrid, Madrid, Spain.
Marina AparicioDepartment of Nutrition and Food Science, Complutense University of Madrid, Madrid, Spain.
Felipe González-MartínezDepartment of Pediatrics, Hospital Universitario Gregorio Marañón, Madrid, Spain.
María Isabel González-SánchezDepartment of Pediatrics, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Jimena Pérez-MorenoDepartment of Pediatrics, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Blanca Toledo Del CastilloDepartment of Pediatrics, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Juan Miguel RodríguezDepartment of Nutrition and Food Science, Complutense University of Madrid, Madrid, Spain.
Rosa Rodríguez-FernándezDepartment of Pediatrics, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Leonides FernándezDepartment of Galenic Pharmacy and Food Technology, Complutense University of Madrid, Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiolitis associated with the respiratory syncytial virus (RSV) is the leading cause of hospitalization among infants aged < 1 year. The main objective of this work was to assess the nasal and fecal microbiota and immune profiles in infants with RSV bronchiolitis, and to compare them with those of healthy infants. For this purpose, a total of 58 infants with RSV-positive bronchiolitis and 17 healthy infants (aged < 18 months) were recruited in this case-control study, which was approved by the Ethics Committee of the Hospital Gregorio Marañón. Nasal and fecal samples were obtained and submitted to bacterial microbiota analysis by 16S rDNA sequencing and to analysis of several immune factors related to inflammatory processes. Nasal samples in which

Indexed as

bacterial microbiotaBAFF/TNFSF13BbronchiolitisHaemophilusimmunoprofilenasal lavagerespiratory syncytial virus

Identifiers

PMID34140944
PMCPMC8203809
OpenAlexW3172964930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.