ArticleInternational journal of nanomedicine2021
Targeting Antibacterial Effect and Promoting of Skin Wound Healing After Infected with Methicillin-Resistant
Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Clindamycin-Loaded Polyhydroxyalkanoate Nanoparticles for the Treatment of Methicillin-ResistantPharmaceutics · 2024Article
- Exploring the underlying pharmacological, immunomodulatory, and anti-inflammatory mechanisms of phytochemicals against wounds: a molecular insight.Inflammopharmacology · 2024Review
- An Overview of Biofilm-Associated Infections and the Role of Phytochemicals and Nanomaterials in Their Control and Prevention.Pharmaceutics · 2024Review
- Study of the Interaction of Ti-Zn as a Mixed Oxide at Different pH Values Synthesized by the Sol-Gel Method and Its Antibacterial Properties.Nanomaterials (Basel, Switzerland) · 2022Article
- Mechanisms of Metallic Nanomaterials to Induce an Antibacterial Effect.Current topics in medicinal chemistry · 2022Review
- In vitro and in vivo Evaluation of the Bioactive Nanofibers-Encapsulated Benzalkonium Bromide for Accelerating Wound Repair with MRSA Skin Infection.International journal of nanomedicine · 2022Article
- The Effect of Gracilaria Corticata and Scenedesmus Acuminates Extract Mixture on the Healing of Wounds Contaminated with Staphylococcus in the Rat Model.Archives of academic emergency medicine · 2022Article
- The Expanded Role of Chitosan in Localized Antimicrobial Therapy.Marine drugs · 2021Review
- The Antibiofilm Nanosystems for Improved Infection Inhibition of Microbes in Skin.Molecules (Basel, Switzerland) · 2021Review
- Antimicrobial Peptide L18R Displays a Modulating Action against Inter-Kingdom Biofilms in the Lubbock Chronic Wound Biofilm Model.Microorganisms · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTopical agents typically remain in the wound site for time duration that are too short to effectively eradicate MRSA tradition formation of BZK that can be maintained within the wound site for longer time periods, should be more effective.
methodsThe novel chitosan and poly (D,L-lactide-co-glycoside) nanoparticles loaded with benzalkonium bromide (BZK) were designed, for the promotion wound healing after MRSA infection. The physical characterization of these nanoparticles, as well as their antibacterial activity in vitro, release profile in simulated wound fluid, cell toxicity, anti-biofilm activity, and their ability to improve the skin wound healing in a mouse model were also studied.
resultsThese novel nanoparticles were found to have a significant antibacterial activity (
conclusionTaken together, these results demonstrated the ability of BZK-loaded nanoparticles in the promotion of skin wound healing with MRSA infection. The current findings open a new avenue for nanomedicine development and future clinical applications in the treatment of wounds.
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Registered trials
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