ArticleNature methods2021
Identification of phosphosites that alter protein thermal stability.
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Article in Nature methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Top-Down Thermal Proteome Profiling (TD-TPP) for Functional Characterization of the Intact Proteoforms in Complex Samples.Journal of mass spectrometry : JMS · 2025Article
- A structural machine learning approach for rapid prediction of thermodynamically destabilizing tyrosine phosphorylations.Cell reports methods · 2025Article
- Unraveling systemic responses to NQO1-activated IB-DNQ and Rucaparib single and dual agent therapy in triple-negative breast cancers.bioRxiv : the preprint server for biology · 2025Article
- Thermal proteome profiling reveals fructose-1,6-bisphosphate as a phosphate donor to activate phosphoglycerate mutase 1.Nature communications · 2024Article
- Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay.Molecular & cellular proteomics : MCP · 2024Article
- Discovery of metal-binding proteins by thermal proteome profiling.Nature chemical biology · 2024Article
- Stability-based approaches in chemoproteomics.Expert reviews in molecular medicine · 2024Review
- Experimental and data analysis advances in thermal proteome profiling.Cell reports methods · 2024Review
- Toward the analysis of functional proteoforms using mass spectrometry-based stability proteomics.Frontiers in analytical science · 2023Article
- Protein-Peptide Turnover Profiling reveals the order of PTM addition and removal during protein maturation.Nature communications · 2022Article
- Rewiring of the protein-protein-metabolite interactome during the diauxic shift in yeast.Cellular and molecular life sciences : CMLS · 2022Article
- IsobaricQuant enables cross-platform quantification, visualization, and filtering of isobarically-labeled peptides.Proteomics · 2022Article
- Article
- Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome.Journal of the American Chemical Society · 2022Article
- A peptidoform based proteomic strategy for studying functions of post-translational modifications.Proteomics · 2022Article
- Strategies for mass spectrometry-based phosphoproteomics using isobaric tagging.Expert review of proteomics · 2021Review
- The rise of proteome-wide biophysics.Molecular systems biology · 2021Article
- Impact of phosphorylation on thermal stability of proteins.Nature methods · 2021Article
- Huang et al. reply.Nature methods · 2021Article
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Authors and funding
6 authors.
Ian R SmithDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-4966-9333
Kyle N HessDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2096-0626
Anna A BakhtinaDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-4550-1135
Anthony S ValenteDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-8641-3775
Ricard A Rodríguez-MiasDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-7960-6387
Judit VillénDepartment of Genome Sciences, University of Washington, Seattle, WA, USA. jvillen@uw.edu.ORCID http://orcid.org/0000-0002-1005-1739
Funding
INTERDISCIPLINARY TRAINING IN GENOMIC SCIENCEST32HG000035 · NHGRI · UNIVERSITY OF WASHINGTON · PI Bruce Colston Trapnell · 1995 to 2026
$24.2MTechnology to understand genetic variant effects in contextRM1HG010461 · NHGRI · UNIVERSITY OF WASHINGTON · PI Douglas M Fowler, Bruce Colston Trapnell · 2019 to 2026
$18.9MEmergent properties of signaling network degradation that mediate homeostatic failure during agingR01AG056359 · NIA · UNIVERSITY OF WASHINGTON · PI KAEBERLEIN, MATT, VILLEN, JUDIT · 2017 to 2021
$2.9MMechanisms of mitochondrial disease suppression in Ndufs4 knockout miceR01NS098329 · NINDS · UNIVERSITY OF WASHINGTON · PI KAEBERLEIN, MATT, VILLEN, JUDIT · 2017 to 2021
$2.4MTowards a comprehensive roadmap of cellular signaling.R35GM119536 · NIGMS · UNIVERSITY OF WASHINGTON · PI VILLEN, JUDIT · 2016 to 2020
$2.2MUniversity of Washington PhD Training in Big Data for Genomics and NeuroscienceT32LM012419 · NLM · UNIVERSITY OF WASHINGTON · PI DANIEL, THOMAS L., FAIRHALL, ADRIENNE L · 2016 to 2019
$1.1MNHGRI NIH HHS RM1 HG010461NHGRI NIH HHS T32 HG000035NIA NIH HHS R01 AG056359NIGMS NIH HHS R35 GM119536NINDS NIH HHS R01 NS098329NLM NIH HHS T32 LM012419
Abstract
PubMed holds no abstract for this paper.
Indexed as
PhosphoproteinsHumansPhosphorylationPhosphoproteins
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.