Evidence map›Paper›PMID 34140685›Full record

ArticleNature genetics2021

PHYTOCHROME-INTERACTING FACTORs trigger environmentally responsive chromatin dynamics in plants.

Björn C Willige, Mark Zander, Chan Yul Yoo, Amy Phan, Renee M Garza, Shelly A Wanamaker, Yupeng He, Joseph R Nery, Huaming Chen, Meng Chen and 2 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Nature genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
19.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.

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  19. Climate change and plant genomic plasticity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Björn C Willige *Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Mark Zander *Plant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Chan Yul YooDepartment of Botany and Plant Sciences, Institute for Integrative Genome Biology, University of California, Riverside, CA, USA.ORCID http://orcid.org/0000-0001-6159-7443
Amy PhanPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Renee M GarzaGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-4581-6161
Shelly A WanamakerGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6904-4149
Yupeng HeGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-9313-614X
Joseph R NeryGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0153-5659
Huaming ChenGenomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Meng ChenDepartment of Botany and Plant Sciences, Institute for Integrative Genome Biology, University of California, Riverside, CA, USA.
Joseph R EckerPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA. ecker@salk.edu.ORCID http://orcid.org/0000-0001-5799-5895
Joanne ChoryPlant Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA. chory@salk.edu.ORCID http://orcid.org/0000-0002-3664-8525
Salk Institute for Biological Studies · USUniversity of California, Riverside · USRutgers, The State University of New Jersey · US

Funding

Genetic Characterization of Phytochrome Nuclear Bodies in Plant Light SignalingR01GM087388 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI CHEN, MENG · 2010 to 2023
$5.8M
Mechanisms Controlling Hormone-Mediated Plant Growth in Response to the EnvironmentR35GM122604 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CHORY, JOANNE · 2017 to 2021
$2.0M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM087388NIGMS NIH HHS R35 GM122604
6 · The paper itself

Abstract

The interplay between light receptors and PHYTOCHROME-INTERACTING FACTORs (PIFs) serves as a regulatory hub that perceives and integrates environmental cues into transcriptional networks of plants

Indexed as

EnvironmentGene-Environment InteractionGene Expression Regulation, PlantBasic Helix-Loop-Helix ProteinsChromatinEpigenesis, GeneticGenetic VariationHistonesProtein Processing, Post-TranslationalBasic Helix-Loop-Helix ProteinsChromatinHistones

Identifiers

PMID34140685
PMCPMC9169284
OpenAlexW3172958954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.