Evidence map›Paper›PMID 34140665›Full record

ReviewNature reviews. Immunology2021

Using cross-species vaccination approaches to counter emerging infectious diseases.

George M Warimwe, Michael J Francis, Thomas A Bowden, Samuel M Thumbi, Bryan Charleston

Abstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Veterinary sciences · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. The active roles ofFrontiers in veterinary science · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Evidence-Based Approach to One Health Vaccinology.Archives of Razi Institute · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

George M WarimweCentre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK. george.warimwe@ndm.ox.ac.uk.ORCID 0000-0002-4911-6333
Michael J FrancisBioVacc Consulting Ltd, Amersham, UK.ORCID 0000-0002-5433-0211
Thomas A BowdenWellcome Centre for Human Genetics, Division of Structural Biology, University of Oxford, Oxford, UK.
Samuel M ThumbiInstitute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK.
Bryan CharlestonThe Pirbright Institute, Woking, UK.

Funding

Medical Research Council MR/S007555/1Wellcome Trust
6 · The paper itself

Abstract

Since the initial use of vaccination in the eighteenth century, our understanding of human and animal immunology has greatly advanced and a wide range of vaccine technologies and delivery systems have been developed. The COVID-19 pandemic response leveraged these innovations to enable rapid development of candidate vaccines within weeks of the viral genetic sequence being made available. The development of vaccines to tackle emerging infectious diseases is a priority for the World Health Organization and other global entities. More than 70% of emerging infectious diseases are acquired from animals, with some causing illness and death in both humans and the respective animal host. Yet the study of critical host-pathogen interactions and the underlying immune mechanisms to inform the development of vaccines for their control is traditionally done in medical and veterinary immunology 'silos'. In this Perspective, we highlight a 'One Health vaccinology' approach and discuss some key areas of synergy in human and veterinary vaccinology that could be exploited to accelerate the development of effective vaccines against these shared health threats.

Indexed as

VaccinationAnimalsCommunicable Diseases, EmergingCOVID-19Cross ReactionsHumansSARS-CoV-2Species SpecificityVaccinesViral ZoonosesVaccines

Identifiers

PMID34140665
PMCPMC8211312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.