ArticleNature ecology & evolution2021
Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.
Article in Nature ecology & evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- A century of theories of balancing selection.Biological reviews of the Cambridge Philosophical Society · 2026Review
- The Interplay of Biotic and Abiotic Factors in Shaping Genetic Variation atEcology and evolution · 2025Article
- Evolutionary Systems Biology Identifies Genetic Trade-offs in Rice Defense against Aboveground and Belowground Attackers.Plant & cell physiology · 2025Article
- Increasing Aridity May Threaten the Maintenance of a Plant Defence Polymorphism.Ecology letters · 2025Article
- Biotic interactions promote local adaptation to soil in plants.Nature communications · 2024Article
- Genetic basis of local adaptation in the cold-tolerant mangroveFrontiers in plant science · 2024Article
- Soil variation among natural habitats alters glucosinolate content in a wild perennial mustard.Journal of experimental botany · 2023Article
- Inferring Balancing Selection From Genome-Scale Data.Genome biology and evolution · 2023Review
- Molecular mechanisms of adaptive evolution in wild animals and plants.Science China. Life sciences · 2023Review
- Globally Relaxed Selection and Local Adaptation in Boechera stricta.Genome biology and evolution · 2022Article
- Ecological factors influence balancing selection on leaf chemical profiles of a wildflower.Nature ecology & evolution · 2021Article
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20 authors.
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Abstract
Balancing selection is frequently invoked as a mechanism that maintains variation within and across populations. However, there are few examples of balancing selection operating on loci underpinning complex traits, which frequently display high levels of variation. We investigated mechanisms that may maintain variation in a focal polymorphism-leaf chemical profiles of a perennial wildflower (Boechera stricta, Brassicaceae)-explicitly interrogating multiple ecological and genetic processes including spatial variation in selection, antagonistic pleiotropy and frequency-dependent selection. A suite of common garden and greenhouse experiments showed that the alleles underlying variation in chemical profile have contrasting fitness effects across environments, implicating two ecological drivers of selection on chemical profile: herbivory and drought. Phenotype-environment associations and molecular genetic analyses revealed additional evidence of past selection by these drivers. Together, these data are consistent with balancing selection on chemical profile, probably caused by pleiotropic effects of secondary chemical biosynthesis genes on herbivore defence and drought response.
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