Evidence map›Paper›PMID 34140413›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

High-resolution multicontrast tomography with an X-ray microarray anode-structured target source.

Guibin Zan, Sheraz Gul, Jin Zhang, Wei Zhao, Sylvia Lewis, David J Vine, Yijin Liu, Piero Pianetta, Wenbing Yun

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Nanoscale chemical imaging with structured X-ray illumination.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
  5. Article
  6. Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. In situ visualization of multicomponents coevolution in a battery pouch cell.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Guibin ZanStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025.
Sheraz GulSigray Inc., Concord, CA 94520.
Jin ZhangStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025.
Wei ZhaoSchool of Physics, Beihang University, 100083 Beijing, China.ORCID 0000-0002-6182-4746
Sylvia LewisSigray Inc., Concord, CA 94520.
David J VineSigray Inc., Concord, CA 94520; dvine@sigray.com liuyijin@slac.stanford.edu.
Yijin LiuStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025; dvine@sigray.com liuyijin@slac.stanford.edu.ORCID 0000-0002-8417-2488
Piero PianettaStanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025.
Wenbing YunSigray Inc., Concord, CA 94520.
Sigray (United States) · USSLAC National Accelerator Laboratory · USBeihang University · CN

Funding

A high brightness microstructured anode X-ray source for clinical phase contrast imagingR44EB023284 · NIBIB · SIGRAY, INC. · PI YUN, WENBING · 2016 to 2018
$1.7M
NIBIB NIH HHS R44 EB023284
6 · The paper itself

Abstract

Multicontrast X-ray imaging with high resolution and sensitivity using Talbot-Lau interferometry (TLI) offers unique imaging capabilities that are important to a wide range of applications, including the study of morphological features with different physical properties in biological specimens. The conventional X-ray TLI approach relies on an absorption grating to create an array of micrometer-sized X-ray sources, posing numerous limitations, including technical challenges associated with grating fabrication for high-energy operations. We overcome these limitations by developing a TLI system with a microarray anode-structured target (MAAST) source. The MAAST features an array of precisely controlled microstructured metal inserts embedded in a diamond substrate. Using this TLI system, tomography of a Drum fish tooth with high resolution and tri-contrast (absorption, phase, and scattering) reveals useful complementary structural information that is inaccessible otherwise. The results highlight the exceptional capability of high-resolution multicontrast X-ray tomography empowered by the MAAST-based TLI method in biomedical applications.

Indexed as

Tomography, X-Ray ComputedAnimalsData AnalysisElectrodesFishesImaging, Three-DimensionalInterferometryLightingToothmicroarray anode–structured targetphase-contrast tomographyTalbot–Lau grating interferometryX-ray source

Identifiers

PMID34140413
PMCPMC8237686
OpenAlexW3168325576

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.