Evidence map›Paper›PMID 34140354›Full record

ArticleGenes & development2021

Epitranscriptomic addition of m

Kevin Tsai, Hal P Bogerd, Edward M Kennedy, Ann Emery, Ronald Swanstrom, Bryan R Cullen

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Review
  3. The mJournal of virology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review
  8. High-resolution HIV-1 mNAR genomics and bioinformatics · 2025
    Article
  9. Single-base mJournal of virology · 2025
    Article
  10. Impact of NbioRxiv : the preprint server for biology · 2025
    Article
  11. mGenes to cells : devoted to molecular & cellular mechanisms · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. YTHDF1 and YTHDC1 mJournal of virology · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kevin TsaiDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.ORCID 0000-0003-1712-9153
Hal P BogerdDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Edward M KennedyDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Ann EmeryLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.ORCID 0000-0002-3610-9548
Ronald SwanstromLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
Bryan R CullenDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.ORCID 0000-0002-8638-6850
Duke University · USUniversity of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
The Center for HIV RNA Studies (CRNA)U54AI150470 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHIU, WAH · 2019 to 2021
$15.1M
Epitranscriptomic modification of HIV-1 transcripts: Effects of drugs of abuseR01DA046111 · NIDA · DUKE UNIVERSITY · PI CULLEN, BRYAN R. · 2018 to 2022
$1.6M
NCI NIH HHS P30 CA016086NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI064518NIAID NIH HHS U54 AI150470NIDA NIH HHS R01 DA046111
6 · The paper itself

Abstract

Previous work has demonstrated that the epitranscriptomic addition of m

Indexed as

HIV-1AdenosineAlternative SplicingRNA-Binding ProteinsRNA SplicingRNA StabilityRNA, ViralAdenosineRNA-Binding ProteinsRNA, Viralepitranscriptomic regulationHIV-1RNARNA stabilitysplicingYTHDC1YTHDF2

Identifiers

PMID34140354
PMCPMC8247604
OpenAlexW3169958738

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.