Evidence map›Paper›PMID 34140277›Full record

ArticleAJNR. American journal of neuroradiology2021

Diagnostic Performance of Conebeam CT Pixel Values in Active Fenestral Otosclerosis.

F Deng, P Touska, K L Reinshagen, H D Curtin, A F Juliano

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Current trends in imaging for otosclerosis and the potential role of photon-counting computed tomography.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025
    Review
  3. Artificial Intelligence for Otosclerosis Detection: A Pilot Study.Journal of imaging informatics in medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

F DengFrom the Department of Radiology (F.D.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-3117-5076
P TouskaDepartment of Radiology (P.T), Guy's Hospital, Guy's and St. Thomas' Hospitals National Health Service Foundation Trust, London, UK.ORCID 0000-0002-9350-0420
K L ReinshagenDepartment of Radiology (K.L.R, H.D.C., A.F.J.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-3705-1082
H D CurtinDepartment of Radiology (K.L.R, H.D.C., A.F.J.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0003-2163-9404
A F JulianoDepartment of Radiology (K.L.R, H.D.C., A.F.J.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts. amy_juliano@meei.harvard.edu.ORCID 0000-0002-5088-5367
Massachusetts Eye and Ear Infirmary · USHarvard University · USNational Health Service · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeQuantitative bone densitometry on multidetector CT of the temporal bone is a diagnostic adjunct for otosclerosis in its active (spongiotic) phase, but translating this technique to conebeam CT is limited by the technical variability of conebeam CT pixel values. The purpose of this study was to evaluate the performance of internally calibrated conebeam CT pixel value measurements that can enable the determination of active fenestral otosclerosis (otospongiosis). MATERIALS AND

methodsThis study included 37 ears in 22 patients with a clinical diagnosis of otospongiosis in those ears and 35 ears in 22 control patients without the diagnosis. Temporal bone conebeam CT was performed. ROIs were set anterior to the oval window, in the lateral semicircular canal bone island, and in a nearby aerated space. Mean conebeam CT pixel values in these regions determined the relative attenuation ratio of the area anterior to the oval window normalized to normal otic capsule bone and air.

resultsThe relative attenuation ratio for cases of otospongiosis was significantly lower than that for controls (

conclusionsInternally calibrated pixel value ratios in temporal bone conebeam CT can feasibly help diagnose active/spongiotic-phase fenestral otosclerosis in an objective manner.

Indexed as

Ear, InnerOtosclerosisCochleaHumansMultidetector Computed TomographyTemporal Bone

Identifiers

PMID34140277
PMCPMC8423045
OpenAlexW3166934993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.