Evidence map›Paper›PMID 34140269›Full record

ArticleBiomedical journal2021

Differential inflammatory response of men and women subjected to an acute resistance exercise.

Jerónimo Aragón-Vela, Luis Fontana, Rafael A Casuso, Julio Plaza-Díaz, Jesús R Huertas

Open access · goldAbstract read
In one paragraph

Article in Biomedical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jerónimo Aragón-VelaDepartment of Physiology, School of Sport Sciences, University of Granada, Spain; Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Centre, University of Granada, Spain. Electronic address: jeroav@ugr.es.
Luis FontanaDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Spain; Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Centre, University of Granada, Spain; Health Research Institute of Granada (ibs.GRANADA), 18010 Granada, Spain.
Rafael A CasusoDepartment of Physiology, School of Sport Sciences, University of Granada, Spain; Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Centre, University of Granada, Spain.
Julio Plaza-DíazDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, Spain; Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Centre, University of Granada, Spain; Health Research Institute of Granada (ibs.GRANADA), 18010 Granada, Spain.
Jesús R HuertasDepartment of Physiology, School of Sport Sciences, University of Granada, Spain; Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Centre, University of Granada, Spain.
Universidad de Granada · ESInstituto de Investigación Biosanitaria de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate the inflammatory response, lipid peroxidation and muscle damage in men and women athletes subjected to an acute resistance exercise.

methodsTwenty college athletes (10 men and 10 women) performed a half-squat exercise consisting of five incremental intensities: 20%, 40%, 60%, 80% and 100% of the one-repetition maximum. Blood samples were collected at rest, 15 min and 24 h post-test. The concentration of lipid peroxidation markers and the activities of a skeletal muscle damage marker and a cardiac muscle damage marker were determined in serum. Serum α-actin was measured as a marker of sarcomere damage. Serum levels of interleukin-6, interleukin-10, and tumor necrosis factor alpha were determined to assess the inflammatory response.

resultsInterleukin-6 levels were higher at 24 h post-test than at rest and 15 min post-test in men (p < 0.05). Moreover, men showed significantly higher hydroperoxide levels in response to resistance exercise at 24 h post-test than at 15 min post-test (p < 0.05). No differences were found in muscle damage parameters regardless of sex or the time point of the test. No differences regarding the studied variables were found when comparing among different time points in women.

conclusionOur results show a larger influence of half-squat exercises on the release of IL6 and on lipid peroxidation in men than in women at equivalent workloads.

Indexed as

Resistance TrainingBiomarkersExerciseFemaleHumansLipid PeroxidationMaleMuscle, SkeletalBiomarkersIL6Inflammatory responseSerum interleukinsSex differencesStrength exercise

Identifiers

PMID34140269
PMCPMC8358195
OpenAlexW3171015811

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.