ArticleOral oncology2021
Implementation of human papillomavirus circulating tumor DNA to identify recurrence during treatment de-escalation.
Abstract readLetter
In one paragraph
Article in Oral oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Early HPV ctDNA Kinetics and Imaging Biomarkers Predict Therapeutic Response in p16+ Oropharyngeal Squamous Cell Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022Trial
- Validation of MyHPVscore: A High-Performance Human Papillomavirus Circulating Tumor DNA Laboratory-Developed Test.The Journal of molecular diagnostics : JMD · 2026Article
- The role of liquid biopsy in the molecular characterization of HPV-related cancers.Folia microbiologica · 2026Review
- Risk of Occult Contralateral Neck Metastasis in Early-Stage HPV-Related Lateralized Cancer of the Base of the Tongue.Head & neck · 2026Article
- HPV Detection in Oropharyngeal Cancer: A Narrative Review of Diagnostic and Emerging Molecular Approaches.Diagnostics (Basel, Switzerland) · 2026Review
- Selection Criteria for De-Escalated Chemoradiotherapy for HPV-Related Oropharyngeal Cancer Based on Prognostic Biomarkers or Early Tumor Response to Therapy: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- The Value of Circulating Tumor HPV DNA in Head and Neck Squamous Cell Cancer: A Review.Diagnostics (Basel, Switzerland) · 2025Review
- Circulating biomarkers in HPV-associated oropharyngeal cancer: Clinical applications of liquid biopsy in diagnosis, prognosis, and surveillance.The journal of liquid biopsy · 2025Review
- A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue-Modified Viral HPV DNA.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Article
- Unraveling Emerging Anal Cancer Clinical Biomarkers from Current Immuno-Oncogenomics Advances.Molecular diagnosis & therapy · 2024Review
- Human papillomavirus circulating tumor DNA assays as a mechanism for head and neck cancer equity in rural regions of the United States.Frontiers in oncology · 2024Review
- Circulating Tumor HPV DNA for Surveillance of HPV-Positive Oropharyngeal Squamous Cell Carcinoma: A Narrative Review.JAMA oncology · 2023Review
- Development of a high-performance multi-probe droplet digital PCR assay for high-sensitivity detection of human papillomavirus circulating tumor DNA from plasma.Oral oncology · 2023Article
- Analysis of Human Papilloma Virus Content and Integration in Mucoepidermoid Carcinoma.Viruses · 2022Article
- De-Escalation Strategies for Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma-Where Are We Now?Current oncology (Toronto, Ont.) · 2022Review
- Tumor-Derived Exosomes and the Role of Liquid Biopsy in Human Papillomavirus Oropharyngeal Squamous Cell Carcinoma.Cancer journal (Sudbury, Mass.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Catherine T HaringUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Collin BrummelUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Chandan BhambhaniUniversity of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States.
Brittany JewellUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Molly Heft NealUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Apurva BhangaleUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States.
Keith CasperUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Kelly MalloyUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Scott McLeanUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Andrew ShumanUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Chaz StuckenUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Andrew RoskoUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Mark PrinceUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Carol BradfordUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
Avraham EisbruchUniversity of Michigan, Department of Radiation Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Michelle MierzwaUniversity of Michigan, Department of Radiation Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Muneesh TewariUniversity of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Francis P WordenUniversity of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Paul L SwiecickiUniversity of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, United States; University of Michigan, Rogel Cancer Center, United States.
Matthew E SpectorUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States.
J Chad BrennerUniversity of Michigan, Department of Otolaryngology- Head and Neck Surgery, United States; University of Michigan, Rogel Cancer Center, United States; University of Michigan, Department of Pharmacology, United States. Electronic address: chadbren@umich.edu.
Funding
XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THEODORE S LAWRENCE · 1988 to 2026
$178.2MNCI NIH HHS P30 CA046592
Abstract
PubMed holds no abstract for this paper.
Indexed as
AlphapapillomavirusCirculating Tumor DNAOropharyngeal NeoplasmsPapillomavirus InfectionsDNA, ViralHumansNeoplasm Recurrence, LocalCirculating Tumor DNADNA, Viral
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.