Evidence map›Paper›PMID 34140183›Full record

ReviewSeminars in arthritis and rheumatism2021

Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group.

Ken Cai, Amy Fuller, Yiling Zhang, Owen Hensey, David Grossberg, Robin Christensen, Beverley Shea, Jasvinder A Singh, Geraldine M McCarthy, Ann K Rosenthal and 13 more

Abstract readReview
In one paragraph

Review in Seminars in arthritis and rheumatism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review: Outcome measures in calcium pyrophosphate deposition.Best practice & research. Clinical rheumatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Ken CaiBone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Auckland, New Zealand. Electronic address: k.cai@auckland.ac.nz.
Amy FullerAcademic Rheumatology, University of Nottingham, Nottingham, United Kingdom; Nottingham NIHR-BRC, Nottingham, United Kingdom.
Yiling ZhangBone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Auckland, New Zealand.
Owen HenseyThe Central Remedial Clinic, Dublin, Ireland.
David GrossbergHoly Cross Hospital, Silver Spring, MD, United States; Suburban Hospital, Bethesda, MD, United States.
Robin ChristensenSection for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen & Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Denmark.
Beverley SheaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
Jasvinder A SinghMedicine Service, VA Medical Center, Birmingham, AL, United States; Department of Medicine at the School of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL, United States; Department of Epidemiology at the UAB School of Public Health, Birmingham, AL, United States.
Geraldine M McCarthyUniversity College Dublin, Dublin, Ireland.
Ann K RosenthalDepartment of Medicine, Medical College of Wisconsin, Milwaukee, United States.
Georgios FilippouRheumatology Unit, ASST-Fatebenefratelli L, Sacco University Hospital, University of Milan, Italy.
William J TaylorDepartment of Medicine, University of Otago, Wellington, New Zealand.
Cesar Diaz-TorneDepartment of Rheumatology, Hospital de la Santa Creu i Sant Pau, Universitat Autonòma de Barcelona, Spain.
Lisa K StampDepartment of Medicine, University of Otago, Christchurch, New Zealand.
N Lawrence EdwardsDepartment of Medicine, University of Florida College of Medicine, Gainesville, Florida, United States.
Tristan PascartDepartment of Rheumatology, Hospital Saint-Philbert, Lille Catholic University, Lille, France.
Fabio BecceDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Sabrina M NielsenSection for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen & Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Denmark.
Peter TugwellDepartment of Medicine, University of Ottawa, Ottawa, Canada.
Dorcas BeatonInstitute for Work and Health, University of Toronto, Toronto, Canada.
Abhishek AbhishekAcademic Rheumatology, University of Nottingham, Nottingham, United Kingdom; Nottingham NIHR-BRC, Nottingham, United Kingdom.
Sara K TedeschiDivision of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Boston, MA, United States.
Nicola DalbethBone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Auckland, New Zealand.

Funding

Studying pseudogout using naturallanguage processing and novelimaging approachesK23AR075070 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI TEDESCHI, SARA K. · 2019 to 2023
$937k
Mutations in Osteoprotegerin Cause Calcium Pyrophosphate Deposition DiseaseI01BX004454 · VA · CLEMENT J. ZABLOCKI VA MEDICAL CENTER · PI ROSENTHAL, ANN K · 2019 to 2025
–
BLRD VA I01 BX004454Department of HealthNIAMS NIH HHS K23 AR075070NIAMS NIH HHS L30 AR070514
6 · The paper itself

Abstract

introductionAlthough calcium pyrophosphate deposition (CPPD) is common, there are no published outcome domains or validated measurement instruments for CPPD studies. In this paper, we describe the framework for development of the Outcome Measures in Rheumatology (OMERACT) CPPD Core Domain Sets.

methodsThe OMERACT CPPD working group performed a scoping literature review and qualitative interview study. Generated outcomes were presented at the 2020 OMERACT CPPD virtual Special Interest Group (SIG) meeting with discussion focused on whether different core domain sets should be developed for different calcium pyrophosphate deposition (CPPD) clinical presentations and how the future CPPD Core Domain Set may overlap with already established osteoarthritis (OA) domains. These discussions informed development of a future work plan for development of the OMERACT CPPD Core Domain Sets.

findingsDomains identified from a scoping review of 112 studies and a qualitative interview study of 36 people (28 patients with CPPD, 7 health care professionals, one stakeholder) were mapped to core areas of OMERACT Filter 2.1. The majority of SIG participants agreed there was need to develop separate core domain sets for "short term" and "long term" studies of CPPD. Although CPPD + OA is common and core domain sets for OA have been established, participants agreed that existing OA core domain sets should not influence the development of OMERACT core domain sets for CPPD. Prioritization exercises (using Delphi methodology) will consider 40 potential domains for short term studies of CPPD and 47 potential domains for long term studies of CPPD.

conclusionSeparate OMERACT CPPD Core Domain Sets will be developed for "short term" studies for an individual flare of acute CPP crystal arthritis and for "long term" studies that may include participants with any clinical presentation of CPPD (acute CPP crystal arthritis, chronic CPP crystal inflammatory arthritis, and/or CPPD + OA).

Indexed as

CalcinosisChondrocalcinosisOsteoarthritisRheumatologyCalcium PyrophosphateHumansCalcium PyrophosphateCalcium pyrophosphate deposition diseaseCPPDDomainsOMERACTOutcomesPseudogout

Identifiers

PMID34140183
PMCPMC8981257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.