Evidence map›Paper›PMID 34140163›Full record

ArticleClinical nutrition (Edinburgh, Scotland)2022

Nutritional management of individuals with obesity and COVID-19: ESPEN expert statements and practical guidance.

Rocco Barazzoni, Stephan C Bischoff, Luca Busetto, Tommy Cederholm, Michael Chourdakis, Cristina Cuerda, Nathalie Delzenne, Laurence Genton, Stephane Schneider, Pierre Singer and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical nutrition (Edinburgh, Scotland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 57 citations in OpenAlex.

  1. Animals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. COVID, the Gut, and Nutritional Implications.Current surgery reports · 2023
    Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 9 countries.

Rocco BarazzoniDepartment of Medical, Surgical and Health Sciences, University of Trieste, Italy; Azienda sanitaria universitaria Giuliano Isontina (ASUGI), Cattinara Hospital, Trieste, Italy. Electronic address: barazzon@units.it.
Stephan C BischoffDepartment of Nutritional Medicine and Prevention, University of Hohenheim, Stuttgart, Germany.
Luca BusettoDepartment of Medicine, University of Padova, Italy.
Tommy CederholmDepartment of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden.
Michael ChourdakisSchool of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.
Cristina CuerdaNutrition Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Nathalie DelzenneLouvain Drug Research Institute, UCLouvain, Brussels, Belgium.
Laurence GentonClinical Nutrition, Geneva University Hospitals, Geneva, Switzerland.
Stephane SchneiderGastroenterology and Nutrition, Nice University Hospital, Université Côte d'Azur, Nice, France.
Pierre SingerDepartment of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Sackler School of Medicine, Tel Aviv University, Israel.
Yves BoirieDepartment of Clinical Nutrition, CHU Clermont-Ferrand, University of Clermont Auvergne, Human Nutrition Unit, CRNH Auvergne, F-63000, Clermont-Ferrand, France.
endorsed by the ESPEN Council
Aristotle University of Thessaloniki · GRHospital General Universitario Gregorio Marañón · ESOspedale di Cattinara · ITRabin Medical Center · ILSolvay (Belgium) · BEUniversité Clermont Auvergne · FRUniversité Côte d'Azur · FRUniversity Hospital of Geneva · CHUniversity of Hohenheim · DEUniversity of Padua · ITUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemics has created unprecedented challenges and threats to patients and healthcare systems worldwide. Acute respiratory complications that require intensive care unit (ICU) management are a major cause of morbidity and mortality in COVID-19 patients. Among other important risk factors for severe COVID-19 outcomes, obesity has emerged along with undernutrition-malnutrition as a strong predictor of disease risk and severity. Obesity-related excessive body fat may lead to respiratory, metabolic and immune derangements potentially favoring the onset of COVID-19 complications. In addition, patients with obesity may be at risk for loss of skeletal muscle mass, reflecting a state of hidden malnutrition with a strong negative health impact in all clinical settings. Also importantly, obesity is commonly associated with micronutrient deficiencies that directly influence immune function and infection risk. Finally, the pandemic-related lockdown, deleterious lifestyle changes and other numerous psychosocial consequences may worsen eating behaviors, sedentarity, body weight regulation, ultimately leading to further increments of obesity-associated metabolic complications with loss of skeletal muscle mass and higher non-communicable disease risk. Therefore, prevention, diagnosis and treatment of malnutrition and micronutrient deficiencies should be routinely included in the management of COVID-19 patients in the presence of obesity; lockdown-induced health risks should also be specifically monitored and prevented in this population. In the current document, the European Society for Clinical Nutrition and Metabolism (ESPEN) aims at providing clinical practice guidance for nutritional management of COVID-19 patients with obesity in various clinical settings.

Indexed as

COVID-19MalnutritionCommunicable Disease ControlHumansMicronutrientsObesityMicronutrientsCOVID-19Nutritional managementObesity

Identifiers

PMID34140163
PMCPMC8110326
OpenAlexW3163516453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.