ReviewSeminars in nephrology2021
The Interplay Between Thyroid Dysfunction and Kidney Disease.
Review in Seminars in nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07663773 (Deciphering the Role of Thyroid Hormones in Severe Non-ADPKD Chronic Kidney Disease), which is not on this map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Deciphering the Role of Thyroid Hormones in Severe Non-ADPKD Chronic Kidney Disease
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Association between hypothyroidism, levothyroxine replacement and kidney function outcomes: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Association between hypothyroidism and risk of chronic kidney disease: evidence from a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Association between central thyroid hormone dysregulation and chronic kidney disease in type 2 diabetes: a cross-sectional study.Renal failure · 2026Article
- Acid-Base Dysregulation Links Aging Metabolism to Frailty.Aging cell · 2026Article
- Kidney diseases and the thyroid: interactions and consequences.Nature reviews. Endocrinology · 2026Review
- Low fT3 Syndrome, Dialysis Inadequacy, and Death Occurrence in Hemodialysis Patients: Evidence of a Vicious Circle from a Prospective Bi-Center Observational Study.Journal of clinical medicine · 2026Article
- Association between thyroid hormone sensitivity indices and renal function in community-dwelling euthyroid older adults: a cross-sectional study.Scientific reports · 2026Article
- Thyroid Hormone Indices and Histopathological Severity of Diabetic Nephropathy in Euthyroid Patients with Type 2 Diabetes: A Biopsy-Based Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Chronic Kidney Disease, Sarcopenia, and Hormonal-Metabolic Alterations: An Intriguing Association.Kidney & blood pressure research · 2026Review
- Dialysis adequacy revisited: Kt/V's blind spot for phosphorus and iodine.Journal of translational internal medicine · 2025Article
- Hormones and Nephrons: Disentangling the Thyroid-Kidney Connection.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Role of subclinical hypothyroidism on kidney damage in children with obesity.International journal of obesity (2005) · 2025Article
- Incidence and Risk Factors for Amiodarone-Induced Thyroid Dysfunction: A Nationwide Retrospective Cohort Study.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025Article
- The association of thyroid hormone levels and incidence of chronic kidney disease: the Tehran thyroid study (TTS).Thyroid research · 2025Article
- Assessment of Renal Function in Patients with Chronic Kidney Disease with and without Hypothyroidism.Ethiopian journal of health sciences · 2025Article
- Diagnostic value of serum TGF-β1 and CysC in type 2 diabetic kidney disease: a cross-sectional study.Frontiers in medicine · 2025Article
- Thyroid Dysfunction in Patients With End-Stage Renal Disease: A Single-Centered Experience From Pakistan.Cureus · 2025Article
- Optimizing Care for Primary Glomerulonephritis: The Role of Thyroid Evaluation.Endocrine, metabolic & immune disorders drug targets · 2025Observational
- Article
- Phosphate Binder Impairs Levothyroxine Absorption in a Hypothyroid Patient With End-Stage Renal Disease.Cureus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Hypothyroidism is a highly prevalent endocrine complication in chronic kidney disease (CKD) patients. A large body of evidence has shown that there is a bidirectional relationship between thyroid dysfunction and kidney disease, yet there are many remaining gaps in knowledge in regards to the clinical management of CKD patients with hypothyroidism, including those receiving hemodialysis and peritoneal dialysis. Given that hypothyroidism has been associated with many deleterious outcomes including a higher risk of (1) mortality, (2) cardiovascular disease, (3) impaired health-related quality of life, and (4) altered body composition in both non-CKD and CKD patients, future research is needed to establish the appropriate screening, diagnosis, and treatment approaches in these populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.