SynthesisSubstance use & misuse2021
Examining the Relationship between Social Connection and Opioid Misuse: A Systematic Review.
Synthesis in Substance use & misuse, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Social disconnection and subsequent mental disorders: a population-based cohort study.Social psychiatry and psychiatric epidemiology · 2026Article
- Using explainable machine learning to elucidate social and neurobehavioral risk factors linked to nonmedicinal opioid use in young adults.Scientific reports · 2025Article
- An Examination of the Relationship Between Social Support Networks and Opioid Misuse Among American Indian/Alaska Native Populations: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Ethnic Identity and Past 30-Day Opioid Misuse: Mediating Effect of Relational Support.Substance use & misuse · 2025Article
- Independent and joint contributions of physical disability and chronic pain to incident opioid use disorder and opioid overdose among Medicaid patients.Psychological medicine · 2024Article
- The role of social connection in opioid use disorder treatment engagement.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
- Pathways to opioid use and implications for prevention: voices of young adults in recovery.Substance abuse treatment, prevention, and policy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
methodsWe used a Boolean search strategy of PubMed, PsycINFO, and Embase to identify eligible publications from January 1990 to March 2020 and narrative analysis to synthesize the evidence.
resultsThe database search identified 1267 independent citations; 29 publications met inclusion criteria. Nearly all the studies demonstrated high risk of bias, most often due to selection and confounding bias. Most of the studies in the review (
conclusionsThis review highlights the importance of social connection as a correlate to opioid misuse. However, the extensive variability among research studies points to a need for standardization of measurement and larger studies with diverse populations to allow for consequential recommendations for prevention or treatment of opioid misuse. Evidence regarding the associations between social connection and opioid misuse or disorder is sparse. We provide suggestions for advancing this research, including clarification of the complex influences between social connections and opioid misuse.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.