Evidence map›Paper›PMID 34139886›Full record

ArticleBrain connectivity2022

Impact of Locus Coeruleus and Its Projections on Memory and Aging.

Jason Langley, Sana Hussain, Daniel E Huddleston, Ilana J Bennett, Xiaoping P Hu

Open access · greenAbstract read
In one paragraph

Article in Brain connectivity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Vulnerability of locus coeruleus connections to aging and Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jason LangleyCenter for Advanced Neuroimaging, University of California Riverside, Riverside, California, USA.ORCID 0000-0001-9412-1265
Sana HussainDepartment of Bioengineering, University of California Riverside, Riverside, California, USA.ORCID 0000-0003-0986-2654
Daniel E HuddlestonDepartment of Neurology, Emory University, Atlanta, Georgia, USA.ORCID 0000-0003-0503-3736
Ilana J BennettDepartment of Psychology, University of California Riverside, Riverside, California, USA.ORCID 0000-0002-5330-4679
Xiaoping P HuCenter for Advanced Neuroimaging, University of California Riverside, Riverside, California, USA.ORCID 0000-0001-7014-5983
University of California, Riverside · USEmory University · US

Funding

MRI Signatures of Neuromelanin and Iron Pathology in ParkinsonismK23NS105944 · NINDS · EMORY UNIVERSITY · PI HUDDLESTON, DANIEL · 2018 to 2022
$963k
High-resolution multimodal imaging of episodic memory networks in aging.R00AG047334 · NIA · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI BENNETT, ILANA JACQUELINE · 2016 to 2018
$737k
Multi-compartment diffusion imaging of hippocampal white and gray matter in agingR21AG054804 · NIA · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI BENNETT, ILANA JACQUELINE · 2017 to 2018
$427k
NIA NIH HHS R00 AG047334NIA NIH HHS R21 AG054804NINDS NIH HHS K23 NS105944
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diffusion Tensor ImagingLocus CoeruleusAgedAgingBrainCognitionHumansagingcentral tegmental tractDTIlocus coeruleusmemory

Identifiers

PMID34139886
PMCPMC9058864
OpenAlexW3129836894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.