Evidence map›Paper›PMID 34139388›Full record

ReviewTransplantation and cellular therapy2021

Biobehavioral Research and Hematopoietic Stem Cell Transplantation: Expert Review from the Biobehavioral Research Special Interest Group of the American Society for Transplantation and Cellular Therapy.

Debra Lynch Kelly, Karen Syrjala, Mallory Taylor, Kelly E Rentscher, Shahrukh Hashmi, William A Wood, Heather Jim, Anna Barata, Kathryn E Flynn, Linda J Burns and 7 more

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Transplantation and cellular therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05694910 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Reiki on Fatigue, Vital Signs and Engraftment in Bone Marrow Transplant Patients

TypeinterventionalSponsorAnkara Medipol UniversityRan2022 to 2023Enrolled42ConditionsBone Marrow Transplant Complications, Fatigue, Vital Signs, ReikiArmsReiki
NCT07516314 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients (ACTivate)

TypeinterventionalSponsorAnthony Sung, MDRan2026 to 2031Enrolled476ConditionsStem Cell Transplant PatientsArmsACTivate sessions
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Debra Lynch KellyDepartment of Biobehavioral Nursing Science, College of Nursing, University of Florida and University of Florida Health Cancer Center, Gainesville, Florida.
Karen SyrjalaBiobehavioral Sciences Department, Fred Hutchinson Cancer Research Center and University of Washington School of Medicine, Seattle, Washington.
Mallory TaylorDivision of Hematology-Oncology, Department of Pediatrics, University of Washington, Seattle, Washington.
Kelly E RentscherCousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California.
Shahrukh HashmiDepartment of Hematology and Onclolgy; Sheikh Shakhbout Medical City/Mayo Clinic, Abu Dhabi, United Arab Emirates.
William A WoodDivision of Hematology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Heather JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.
Anna BarataDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.
Kathryn E FlynnDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Linda J BurnsCenter for International Blood and Marrow Transplant Research, Milwaukee, Wisconsin.
Bronwen E ShawCenter for International Blood and Marrow Transplantation Research, Froedtert and the Medical College of Wisconsin, Milwaukee, Wisconsin.
Effie PetersdorfClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Anela Carrazana YeroDepartment of Biobehavioral Nursing Science, University of Florida, Gainesville, Florida.
Amanda D EmmrichDepartment of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Keayra E MorrisDepartment of Psychiatry, Medical College of Wisconsin, Milwaukee, Wisconsin.
Erin S CostanzoDepartment of Psychiatry and Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.
Jennifer M KnightDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin; Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: jmknight@mcw.edu.

Funding

Integrating health informatics in a scalable stepped care self-management program for survivors after hematopoietic cell transplantationR01CA215134 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S, MAJHAIL, NAVNEET S. · 2017 to 2022
$3.6M
Improving Survivorship Care for Adolescents and Young Adults: a Mixed Methods Study of Alignment with the National Standards for Survivorship CareU01CA246659 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BAKER, KEVIN S · 2020 to 2025
$3.6M
NCI NIH HHS R01 CA215134NCI NIH HHS U01 CA246659
6 · The paper itself

Abstract

Hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for many hematologic conditions. Despite advances in conditioning and supportive measures, however, there remain significant comorbidities that threaten survivorship. Adverse effects of stress-related biobehavioral processes-defined here as the interactions of behavioral, psychological, and socioenvironmental factors with biology-impact immune recovery and function and are particularly salient in the HCT context, given the importance of immune reconstitution for improved survivorship. However, biobehavioral processes have been underinvestigated in this vulnerable group compared with other cancer populations. Here the Biobehavioral Research Special Interest Group (SIG) of the American Society for Transplantation and Cellular Therapy provides an expert review to inform research directions explicating the biological correlates of behavioral symptoms and evaluate the impact of these on HCT outcomes. The goal of this expert review is to provide a foundation for advancing science that effectively integrates behavioral and biological processes to optimize quality of life and improve clinical outcomes for HCT recipients.

Indexed as

Hematopoietic Stem Cell TransplantationImmune ReconstitutionCell- and Tissue-Based TherapyPublic OpinionQuality of LifeUnited StatesBiobehavioralhematopoietic cell transplantationoutcomesstresssurvivorship

Identifiers

PMID34139388
PMCPMC8428782

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.